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Literature DB >> 9835882

Sudden death in a patient with chronic lymphocytic leukemia.

Abstract

The authors describe a 51-year-old man with chronic lymphocytic leukemia who presented with respiratory distress and then died suddenly while in hospital. Autopsy revealed pulmonary leukostasis and a large intracardiac mass containing mostly mature lymphocytes and fibrin. Although leukostasis and lymphocyte thrombi have been described (albeit rarely) in chronic lymphocytic leukemia, an intracardiac "clot" has not. It seems plausible that this intracardiac mass caused the patient's death.

Entities: Disease Species

Mesh：

Year: 1998 PMID： 9835882 PMCID： PMC1229781

Source DB: PubMed Journal: CMAJ ISSN： 0820-3946 Impact factor: 8.262

11 in total

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Authors: I W Flinn; M R Grever
Journal: Cancer Treat Rev Date: 1996-01 Impact factor: 12.111

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Journal: Blut Date: 1988-01

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Authors: C W de Fijter; J Schuur; B J Potter van Loon; W P Kingma; M J Schweitzer
Journal: Neth J Med Date: 1996-07 Impact factor: 1.422

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Authors: L C McKee; R D Collins
Journal: Medicine (Baltimore) Date: 1974-11 Impact factor: 1.889

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Authors: H S Jacob; P R Craddock; D E Hammerschmidt; C F Moldow
Journal: N Engl J Med Date: 1980-04-03 Impact factor: 91.245

6. The Budd-Chiari syndrome caused by a zygomycete. A new pathogenesis of hepatic vein thrombosis.

Authors: J H Vallaeys; M M Praet; H J Roels; E Van Marck; L Kaufman
Journal: Arch Pathol Lab Med Date: 1989-10 Impact factor: 5.534

7. Rheology of leukocytes, leukocyte suspensions, and blood in leukemia. Possible relationship to clinical manifestations.

Authors: M A Lichtman
Journal: J Clin Invest Date: 1973-02 Impact factor: 14.808

Sudden death in a patient with chronic lymphocytic leukemia.

Review 1. Chronic lymphocytic leukemia.

2. Leucostasis, an underestimated cause of death in leukaemia.

3. Acute cardiorespiratory failure as presenting symptom of chronic lymphocytic leukemia.

4. Intravascular leukocyte thrombi and aggregates as a cause of morbidity and mortality in leukemia.

Review 5. Complement-induced granulocyte aggregation: an unsuspected mechanism of disease.

6. The Budd-Chiari syndrome caused by a zygomycete. A new pathogenesis of hepatic vein thrombosis.

7. Rheology of leukocytes, leukocyte suspensions, and blood in leukemia. Possible relationship to clinical manifestations.

8. [Therapeutic leukapheresis in a leukostasis syndrome complicating chronic lymphoid leukemia].

9. Pulmonary leukostasis: radiologic-pathologic study.

10. Therapeutic cytapheresis in chronic lymphocytic leukemia.

1. Sudden death due to leukostasis in a subject with undiagnosed chronic lymphocytic leukemia.

2. Leukostasis in Chronic Lymphocytic Leukemia.