Literature DB >> 9835298

The sleep of abstinent pure primary alcoholic patients: natural course and relationship to relapse.

S P Drummond1, J C Gillin, T L Smith, A DeModena.   

Abstract

Sleep in male pure primary alcoholic inpatients was examined at a mean of 16 days (n = 29), 19 weeks (n = 29), 14 months (n = 9), and 27 months (n = 4) of abstinence. Results were as follows: (1) the sleep of abstinent alcoholic patients is short, fragmented, and shallow early in abstinence; (2) a patient's sleep improves slowly over at least the first year of abstinence; however, (3) some facets of a patient's sleep remain abnormal even after 27 months of abstinence; (4) insomnia and sleep fragmentation after approximately 5 months of abstinence may be related to relapse by 14 months. The mechanism underlying the relationship between sleep and withdrawal in alcoholic patients is not well understood, and the issue of treating sleep problems as an adjunct to prevention of relapse warrants further investigation.

Entities:  

Mesh:

Year:  1998        PMID: 9835298

Source DB:  PubMed          Journal:  Alcohol Clin Exp Res        ISSN: 0145-6008            Impact factor:   3.455


  102 in total

Review 1.  Chronic alcohol neuroadaptation and stress contribute to susceptibility for alcohol craving and relapse.

Authors:  George R Breese; Rajita Sinha; Markus Heilig
Journal:  Pharmacol Ther       Date:  2010-10-15       Impact factor: 12.310

Review 2.  Mechanisms underlying sleep-wake disturbances in alcoholism: focus on the cholinergic pedunculopontine tegmentum.

Authors:  Clifford M Knapp; Domenic A Ciraulo; Subimal Datta
Journal:  Behav Brain Res       Date:  2014-08-20       Impact factor: 3.332

3.  Perception of sleep in recovering alcohol-dependent patients with insomnia: relationship with future drinking.

Authors:  Deirdre A Conroy; J Todd Arnedt; Kirk J Brower; Stephen Strobbe; Flavia Consens; Robert Hoffmann; Roseanne Armitage
Journal:  Alcohol Clin Exp Res       Date:  2006-12       Impact factor: 3.455

Review 4.  Alcohol use disorder and sleep disturbances: a feed-forward allostatic framework.

Authors:  George F Koob; Ian M Colrain
Journal:  Neuropsychopharmacology       Date:  2019-06-24       Impact factor: 7.853

Review 5.  Treatment options for sleep disturbances during alcohol recovery.

Authors:  J Todd Arnedt; Deirdre A Conroy; Kirk J Brower
Journal:  J Addict Dis       Date:  2007

Review 6.  Psychiatric disorders and sleep.

Authors:  Andrew D Krystal
Journal:  Neurol Clin       Date:  2012-11       Impact factor: 3.806

Review 7.  Alcohol disrupts sleep homeostasis.

Authors:  Mahesh M Thakkar; Rishi Sharma; Pradeep Sahota
Journal:  Alcohol       Date:  2014-11-11       Impact factor: 2.405

Review 8.  Sleep therapeutics and neuropsychiatric illness.

Authors:  Andrew D Krystal
Journal:  Neuropsychopharmacology       Date:  2019-08-03       Impact factor: 7.853

Review 9.  [The importance of sleep for healthy alcohol consumers and alcohol dependent patients].

Authors:  H Gann; D van Calker; B Feige; D Riemann
Journal:  Nervenarzt       Date:  2004-05       Impact factor: 1.214

10.  Tumor necrosis factor antagonism normalizes rapid eye movement sleep in alcohol dependence.

Authors:  Michael R Irwin; Richard Olmstead; Edwin M Valladares; Elizabeth Crabb Breen; Cindy L Ehlers
Journal:  Biol Psychiatry       Date:  2009-01-29       Impact factor: 13.382

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