Literature DB >> 9835147

Synthesis and antimicrobial activity of N-Mannich bases of 3-[N'-sulphadoximino] isatin and its methyl derivative.

N Pandeya, P Yogeeswari, D S Ram, G Nath.   

Abstract

Schiff's bases of isatin and 5-methyl isatin with sulphadoxine and then its N-Mannich bases were synthesised and evaluated for their anti-microbial activity. The piperidonemethyl group improved the activity and most of the compounds were more potent than the pure drugs.

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Year:  1998        PMID： 9835147

Source DB:  PubMed          Journal:  Boll Chim Farm        ISSN： 0006-6648


  3 in total

1.  Synthesis, antibacterial, antifungal and antiviral activity evaluation of some new bis-Schiff bases of isatin and their derivatives.

Authors:  Aliasghar Jarrahpour; Dariush Khalili; Erik De Clercq; Chanaz Salmi; Jean Michel Brunel
Journal:  Molecules       Date:  2007-08-07       Impact factor: 4.411

2.  Synthesis, Spectroscopic Characterization and Antimicrobial Potential of Certain New Isatin-Indole Molecular Hybrids.

Authors:  Reem I Al-Wabli; Azza S Zakaria; Mohamed I Attia
Journal:  Molecules       Date:  2017-11-15       Impact factor: 4.411

3.  Synthesis and biological evaluation of 2-(5-substituted-1-((diethylamino)methyl)-2-oxoindolin-3-ylidene)-N-substituted-hydrazinecarbothioamides.

Authors:  Subhas S Karki; Amol A Kulkarni; Sujeet Kumar; Suresh Kumar Veliyath; Erik De Clercq; Jan Balzarini
Journal:  Med Chem Res       Date:  2012-08-26       Impact factor: 1.965
  3 in total

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