Literature DB >> 9835125

[Prognostic factors in colorectal adenocarcinoma].

F Lagautrière1, L Valvano, M Chaazl, D Benchimol, J L Bernard, A Bourgeon, H Richelme.   

Abstract

Aim of this study was to analyse prognostic factors of improved survival after resection of colorectal cancer. We studied 715 patients by retrospective review operated for colorectal adenocarcinoma. Survival was analyzed by the Kaplan-Maier method. Comparisons were made by log rank analysis. The overall survival is 75% at 1 years, 41.0% at 5 years, 29.7% at 10 years. A significant difference was noted in the survival rate according to age of the patients (p < 0.01), preoperative serum level of carcinoembryonic antigen (CEA) (p < 0.05), the performance status (p < 0.05), intestinal obstruction (p < 0.01), clinicopathological stage of the tumour (p < 0.05). Other factors including the sex, the clinical diagnosis of anaemia, the site of the tumour and histological grade had no apparent influence on survival. To define high-risk groups of recurrence is important for adjuvant therapy and follow-up study.

Entities:  

Mesh:

Year:  1998        PMID: 9835125

Source DB:  PubMed          Journal:  Ann Ital Chir        ISSN: 0003-469X            Impact factor:   0.766


  4 in total

1.  Feasibility and efficacy of capecitabine and FOLFIRI in patients aged 65 years and older with advanced colorectal cancer: a retrospective analysis.

Authors:  Rafał Stec; Lubomir Bodnar; Cezary Szczylik
Journal:  J Cancer Res Clin Oncol       Date:  2009-08-20       Impact factor: 4.553

2.  Low Expression of DYRK2 (Dual Specificity Tyrosine Phosphorylation Regulated Kinase 2) Correlates with Poor Prognosis in Colorectal Cancer.

Authors:  Haiyan Yan; Kaishun Hu; Wenjing Wu; Yu Li; Huan Tian; Zhonghua Chu; H Phillip Koeffler; Dong Yin
Journal:  PLoS One       Date:  2016-08-17       Impact factor: 3.240

3.  K-Ras gene mutation status as a prognostic and predictive factor in patients with colorectal cancer undergoing irinotecan- or oxaliplatin-based chemotherapy.

Authors:  Rafał Stec; Lubomir Bodnar; Radosław Charkiewicz; Jan Korniluk; Marta Rokita; Marta Smoter; Marzena Ciechowicz; Lech Chyczewski; Jacek Nikliński; Wojciech Kozłowski; Cezary Szczylik
Journal:  Cancer Biol Ther       Date:  2012-08-22       Impact factor: 4.742

4.  New insights into the role of age and carcinoembryonic antigen in the prognosis of colorectal cancer.

Authors:  P G Gobbi; F Valentino; E Berardi; C Tronconi; S Brugnatelli; O Luinetti; R Moratti; G R Corazza
Journal:  Br J Cancer       Date:  2007-11-20       Impact factor: 7.640

  4 in total

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