Literature DB >> 9834167

Baicalein, an alpha-glucosidase inhibitor from Scutellaria baicalensis.

T Nishioka1, J Kawabata, Y Aoyama.   

Abstract

Methanol extracts of Scutellaria baicalensis, Rheum officinale, and Paeonia suffruticosa showed potent inhibitory activity against rat intestinal sucrase. The active principles were identified as baicalein from the first and methyl gallate from the last two plants. In addition to its activity against the rat enzyme, baicalein also inhibited human intestinal sucrase expressed in Caco-2 cells.

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Year:  1998        PMID: 9834167     DOI: 10.1021/np980163p

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  26 in total

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