| Literature DB >> 9833882 |
V Gouvea1, N Snellings, M J Popek, C F Longer, B L Innis.
Abstract
The complete nucleotide sequence of the Nepali strain TK15/92 of hepatitis E (HEV) was determined. It showed the highest sequence homology with the Burmese B1 strain, but closer evolutionary relatedness to the Indian strains. Difficulties in reverse-transcribing and amplifying the hypervariable region in ORF1 suggested that strong secondary structures might be intrinsically responsible for the high mutational rate observed in this region of the HEV genome.Entities:
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Year: 1998 PMID: 9833882 DOI: 10.1016/s0168-1702(98)00079-3
Source DB: PubMed Journal: Virus Res ISSN: 0168-1702 Impact factor: 3.303