Literature DB >> 9831256

Androgen-dependent modulation of calbindin-D28K in hypothalamic tissue during prenatal development.

M A Watson1, H Taylor, E D Lephart.   

Abstract

We examined the influence of androgens on fetal medial basal hypothalamic and preoptic area (MBH-POA) calbindin-D28K levels (via Western analysis) by treating pregnant rats with testosterone or flutamide, (an androgen receptor blocker). MBH-POA calbindin-D28K levels were significantly decreased in flutamide-treated male fetuses, whereas, MBH-POA calbindin-D28K levels were significantly increased in testosterone-treated female fetuses compared to controls. These results suggest that MBH-POA calbindin-D28K is modulated during prenatal development by androgens.

Entities:  

Mesh：

Substances：

Year:  1998        PMID： 9831256     DOI： 10.1016/s0168-0102(98)00068-6

Source DB:  PubMed          Journal:  Neurosci Res        ISSN： 0168-0102            Impact factor:   3.304


  5 in total

Review 1.  Estrogenic environmental endocrine-disrupting chemical effects on reproductive neuroendocrine function and dysfunction across the life cycle.

Authors:  Sarah M Dickerson; Andrea C Gore
Journal:  Rev Endocr Metab Disord       Date:  2007-06       Impact factor: 6.514

Review 2.  Location, location, location: genetic regulation of neural sex differences.

Authors:  Jean LeBeau Abel; Emilie F Rissman
Journal:  Rev Endocr Metab Disord       Date:  2012-09       Impact factor: 6.514

Review 3.  Surprising origins of sex differences in the brain.

Authors:  Margaret M McCarthy; Lindsay A Pickett; Jonathan W VanRyzin; Katherine E Kight
Journal:  Horm Behav       Date:  2015-04-25       Impact factor: 3.587

4.  Neuronal nitric oxide synthase and calbindin delineate sex differences in the developing hypothalamus and preoptic area.

Authors:  Michelle Edelmann; Cory Wolfe; Elka M Scordalakes; Emilie F Rissman; Stuart Tobet
Journal:  Dev Neurobiol       Date:  2007-09-01       Impact factor: 3.964

5.  Visual spatial memory is enhanced in female rats (but inhibited in males) by dietary soy phytoestrogens.

Authors:  T D Lund; T W West; L Y Tian; L H Bu; D L Simmons; K D Setchell; H Adlercreutz; E D Lephart
Journal:  BMC Neurosci       Date:  2001-12-17       Impact factor: 3.288
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.