Literature DB >> 9826132

Localization of lectin-binding sites on the surface of Trypanosoma cruzi grown in chemically defined conditions.

S C Bourguignon1, W de Souza, T Souto-Padrón.   

Abstract

The transformation of Trypanosoma cruzi epimastigotes to mammal-infective metacyclic trypomastigotes (metacyclogenesis) can be performed in vitro under chemically defined conditions (TAU 3AAG medium). During this process, changes in the nature of cell surface sugar composition and sugar distribution was evaluated using FITC and gold-labeled lectins and observed by flow cytometry and transmission electron microscopy. The pattern of labeling with the lectins from Triticum vulgaris (WGA), Arachis hypogaea (PNA), Limax flavus (LFA), Canavalia ensiformis (Con-A), and Ricinus communis (RCA-I) significantly changed during the metacyclogenic process. The results obtained are discussed in relation to the role played by T. cruzi cell surface carbohydrate residues on the process of parasite-host cell interaction.

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Year:  1998        PMID： 9826132     DOI： 10.1007/s004180050314

Source DB:  PubMed          Journal:  Histochem Cell Biol        ISSN： 0948-6143            Impact factor:   4.304


  17 in total

1.  Calcium-sensitive pyruvate dehydrogenase phosphatase is required for energy metabolism, growth, differentiation, and infectivity of Trypanosoma cruzi.

Authors:  Noelia Lander; Miguel A Chiurillo; Mayara S Bertolini; Melissa Storey; Anibal E Vercesi; Roberto Docampo
Journal:  J Biol Chem       Date:  2018-09-19       Impact factor: 5.157

2.  Oral exposure to Trypanosoma cruzi elicits a systemic CD8⁺ T cell response and protection against heterotopic challenge.

Authors:  Matthew H Collins; Julie M Craft; Juan M Bustamante; Rick L Tarleton
Journal:  Infect Immun       Date:  2011-05-31       Impact factor: 3.441

3.  Mechanism of Trypanosoma cruzi death induced by Cratylia mollis seed lectin.

Authors:  M P Fernandes; N M Inada; M R Chiaratti; F F B Araújo; F V Meirelles; M T S Correia; L C B B Coelho; M J M Alves; F R Gadelha; A E Vercesi
Journal:  J Bioenerg Biomembr       Date:  2010-02-13       Impact factor: 2.945

4.  In vitro and in vivo high-throughput assays for the testing of anti-Trypanosoma cruzi compounds.

Authors:  Adriana M C Canavaci; Juan M Bustamante; Angel M Padilla; Cecilia M Perez Brandan; Laura J Simpson; Dan Xu; Courtney L Boehlke; Rick L Tarleton
Journal:  PLoS Negl Trop Dis       Date:  2010-07-13

5.  Differences between Naegleria fowleri and Naegleria gruberi in expression of mannose and fucose glycoconjugates.

Authors:  Isaac Cervantes-Sandoval; José Jesús Serrano-Luna; Judith Pacheco-Yépez; Angélica Silva-Olivares; Víctor Tsutsumi; Mineko Shibayama
Journal:  Parasitol Res       Date:  2010-01-23       Impact factor: 2.289

6.  Golgi UDP-GlcNAc:polypeptide O-α-N-Acetyl-d-glucosaminyltransferase 2 (TcOGNT2) regulates trypomastigote production and function in Trypanosoma cruzi.

Authors:  Carolina M Koeller; Hanke van der Wel; Christa L Feasley; Fernanda Abreu; Juliana Dutra Barbosa da Rocha; Fabrício Montalvão; Patrícia Fampa; Flávia C G Dos Reis; Georgia C Atella; Thaís Souto-Padrón; Christopher M West; Norton Heise
Journal:  Eukaryot Cell       Date:  2014-08-01

7.  In vitro and in vivo documentation of quantum dots labeled Trypanosoma cruzi--Rhodnius prolixus interaction using confocal microscopy.

Authors:  Denise Feder; Suzete A O Gomes; André A de Thomaz; Diogo B Almeida; Wagner M Faustino; Adriana Fontes; Cecília V Stahl; Jacenir R Santos-Mallet; Carlos L Cesar
Journal:  Parasitol Res       Date:  2009-09-16       Impact factor: 2.289

8.  Utilizing Chemical Genomics to Identify Cytochrome b as a Novel Drug Target for Chagas Disease.

Authors:  Shilpi Khare; Steven L Roach; S Whitney Barnes; Dominic Hoepfner; John R Walker; Arnab K Chatterjee; R Jeffrey Neitz; Michelle R Arkin; Case W McNamara; Jaime Ballard; Yin Lai; Yue Fu; Valentina Molteni; Vince Yeh; James H McKerrow; Richard J Glynne; Frantisek Supek
Journal:  PLoS Pathog       Date:  2015-07-17       Impact factor: 6.823

9.  Perimicrovillar membrane assembly: the fate of phospholipids synthesised by the midgut of Rhodnius prolixus.

Authors:  Paula Rêgo Bittencourt-Cunha; Livia Silva-Cardoso; Giselle Almeida de Oliveira; José Roberto da Silva; Alan Barbosa da Silveira; George Eduardo Gabriel Kluck; Michele Souza-Lima; Katia Calp Gondim; Marilvia Dansa-Petretsky; Carlos Peres Silva; Hatisaburo Masuda; Mario Alberto Cardoso da Silva Neto; Georgia Correa Atella
Journal:  Mem Inst Oswaldo Cruz       Date:  2013-06       Impact factor: 2.743

10.  Rab11 regulates trafficking of trans-sialidase to the plasma membrane through the contractile vacuole complex of Trypanosoma cruzi.

Authors:  Sayantanee Niyogi; Juan Mucci; Oscar Campetella; Roberto Docampo
Journal:  PLoS Pathog       Date:  2014-06-26       Impact factor: 6.823
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