| Literature DB >> 9826112 |
F de Bustos1, F J Jiménez-Jiménez, J A Molina, J Esteban, A Guerrero-Sola, M Zurdo, M Ortí-Pareja, A Tallón-Barranco, C Gómez-Escalonilla, C Ramírez-Ramos, J Arenas, R Enríquez de Salamanca.
Abstract
We compared CSF and serum levels, and the CSF/serum ratio of alpha-tocopherol (vitamin E), measured by HPLC, in 30 patients with sporadic amyotrophic lateral sclerosis (SALS) and 78 matched controls. The mean CSF and serum vitamin E levels did not differ significantly between the 2 study groups. These values were not influenced by the clinical form (spinal versus bulbar) of SALS. CSF alpha-tocopherol levels did not correlate with age, age at onset, and duration of the disease. These results suggest that CSF and serum alpha-tocopherol concentrations are unrelated with the risk for ALS.Entities:
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Year: 1998 PMID： 9826112 DOI： 10.1007/s007020050089
Source DB: PubMed Journal: J Neural Transm (Vienna) ISSN： 0300-9564 Impact factor: 3.575