Literature DB >> 9825480

The potential role of somatostatin analogues in breast cancer treatment.

M Pollak1.   

Abstract

Existing treatments for breast cancer are helpful for many patients, but treatment failure remains a common event, and there is a strong clinical need to improve upon current therapies. Somatostatin analogues have been evaluated for antineoplastic activity in model systems over the past decade, and encouraging results have been obtained (reviewed in [1, 2]). This has led to suggestions to test these agents clinically in the treatment of breast cancer patients, and a program of clinical trials has recently been initiated. This review will describe aspects of research in this area.

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Year:  1997        PMID： 9825480      PMCID： PMC2589265     

Source DB:  PubMed          Journal:  Yale J Biol Med        ISSN： 0044-0086


  37 in total

Review 1.  Breast cancer risk in Japanese women with special reference to the growth hormone-insulin-like growth factor axis.

Authors:  B A Stoll
Journal:  Jpn J Clin Oncol       Date:  1992-02       Impact factor: 3.019

Review 2.  Diet, body size, and breast cancer.

Authors:  D J Hunter; W C Willett
Journal:  Epidemiol Rev       Date:  1993       Impact factor: 6.222

Review 3.  The insulin-like growth factors.

Authors:  W S Cohick; D R Clemmons
Journal:  Annu Rev Physiol       Date:  1993       Impact factor: 19.318

4.  Tamoxifen attenuates pulsatile growth hormone secretion: mediation in part by somatostatin.

Authors:  G S Tannenbaum; W Gurd; M Lapointe; M Pollak
Journal:  Endocrinology       Date:  1992-06       Impact factor: 4.736

5.  In vivo inhibition of insulin-like growth factor I gene expression by tamoxifen.

Authors:  H T Huynh; E Tetenes; L Wallace; M Pollak
Journal:  Cancer Res       Date:  1993-04-15       Impact factor: 12.701

6.  Octreotide stimulates insulin-like growth factor-binding protein-1: a potential pituitary-independent mechanism for drug action.

Authors:  S Ezzat; S G Ren; G D Braunstein; S Melmed
Journal:  J Clin Endocrinol Metab       Date:  1992-12       Impact factor: 5.958

7.  Serum insulin-like growth factor-I in 1030 healthy children, adolescents, and adults: relation to age, sex, stage of puberty, testicular size, and body mass index.

Authors:  A Juul; P Bang; N T Hertel; K Main; P Dalgaard; K Jørgensen; J Müller; K Hall; N E Skakkebaek
Journal:  J Clin Endocrinol Metab       Date:  1994-03       Impact factor: 5.958

Review 8.  Somatostatin analogs for diagnosis and treatment of cancer.

Authors:  G Weckbecker; F Raulf; B Stolz; C Bruns
Journal:  Pharmacol Ther       Date:  1993-11       Impact factor: 12.310

9.  Somatostatin-receptor scintigraphy in primary breast cancer.

Authors:  C H van Eijck; E P Krenning; A Bootsma; H Y Oei; R van Pel; J Lindemans; J Jeekel; J C Reubi; S W Lamberts
Journal:  Lancet       Date:  1994-03-12       Impact factor: 79.321

10.  Stimulation of tyrosine phosphatase and inhibition of cell proliferation by somatostatin analogues: mediation by human somatostatin receptor subtypes SSTR1 and SSTR2.

Authors:  L Buscail; N Delesque; J P Estève; N Saint-Laurent; H Prats; P Clerc; P Robberecht; G I Bell; C Liebow; A V Schally
Journal:  Proc Natl Acad Sci U S A       Date:  1994-03-15       Impact factor: 11.205
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  3 in total

1.  Synthesis, Antitumor and Antibacterial Studies of New Shortened Analogues of (KLAKLAK)2-NH2 and Their Conjugates Containing Unnatural Amino Acids.

Authors:  Sirine Jaber; Ivan Iliev; Tsvetelina Angelova; Veronica Nemska; Inna Sulikovska; Emilia Naydenova; Nelly Georgieva; Ivan Givechev; Ivo Grabchev; Dancho Danalev
Journal:  Molecules       Date:  2021-02-08       Impact factor: 4.411

2.  Synthesis and Biological Studies on (KLAKLAK)2-NH2 Analog Containing Unnatural Amino Acid β-Ala and Conjugates with Second Pharmacophore.

Authors:  Sirine Jaber; Veronica Nemska; Ivan Iliev; Elena Ivanova; Tsvetelina Foteva; Nelly Georgieva; Ivan Givechev; Emilia Naydenova; Veronika Karadjova; Dancho Danalev
Journal:  Molecules       Date:  2021-12-02       Impact factor: 4.411

3.  A review of the use of somatostatin analogs in oncology.

Authors:  Ozge Keskin; Suayib Yalcin
Journal:  Onco Targets Ther       Date:  2013-04-26       Impact factor: 4.147
  3 in total

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