Literature DB >> 9824589

Abscopal regression of hepatocellular carcinoma after radiotherapy for bone metastasis.

K Ohba1, K Omagari, T Nakamura, N Ikuno, S Saeki, I Matsuo, H Kinoshita, J Masuda, H Hazama, I Sakamoto, S Kohno.   

Abstract

Spontaneous regression of hepatocellular carcinoma is a rare phenomenon. Abscopal regression of tumours resulting from the effect of irradiation of a tissue on a remote non-irradiated tissue is also rare. The case of a 76 year old Japanese man with hepatocellular carcinoma that regressed after radiotherapy for thoracic vertebral bone metastasis is described. Serum levels of tumour necrosis factor-alpha increased after radiotherapy. The findings suggests that such abscopal related regression may be associated with host immune response, involving cytokines such as tumour necrosis factor-alpha.

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Year:  1998        PMID: 9824589      PMCID: PMC1727260          DOI: 10.1136/gut.43.4.575

Source DB:  PubMed          Journal:  Gut        ISSN: 0017-5749            Impact factor:   23.059


  93 in total

1.  Spontaneous regression of hepatocellular cancer: case report and review of literature.

Authors:  Navanshu Arora; Sheshadri Madhusudhana
Journal:  Gastrointest Cancer Res       Date:  2011-07

Review 2.  The abscopal effect of local radiotherapy: using immunotherapy to make a rare event clinically relevant.

Authors:  Kobe Reynders; Tim Illidge; Shankar Siva; Joe Y Chang; Dirk De Ruysscher
Journal:  Cancer Treat Rev       Date:  2015-03-28       Impact factor: 12.111

3.  Abscopal regression of antigen disparate tumors by antigen cascade after systemic tumor vaccination in combination with local tumor radiation.

Authors:  James W Hodge; Hadley J Sharp; Sofia R Gameiro
Journal:  Cancer Biother Radiopharm       Date:  2012-01-27       Impact factor: 3.099

Review 4.  Current concepts of immune based treatments for patients with HCC: from basic science to novel treatment approaches.

Authors:  Tim F Greten; Xin W Wang; Firouzeh Korangy
Journal:  Gut       Date:  2015-02-09       Impact factor: 23.059

5.  Will radiation-induced bystander effects or adaptive responses impact on the shape of the dose response relationships at low doses of ionizing radiation?

Authors:  William F Morgan
Journal:  Dose Response       Date:  2006-08-25       Impact factor: 2.658

Review 6.  Spontaneous regression of hepatocellular carcinoma: three case reports and a categorized review of the literature.

Authors:  Susana Oquiñena; Mercedes Iñarrairaegui; Juan J Vila; Felix Alegre; Jose M Zozaya; Bruno Sangro
Journal:  Dig Dis Sci       Date:  2008-08-21       Impact factor: 3.199

7.  Radiation and immunotherapy: a synergistic combination.

Authors:  Anusha Kalbasi; Carl H June; Naomi Haas; Neha Vapiwala
Journal:  J Clin Invest       Date:  2013-07-01       Impact factor: 14.808

Review 8.  Health risks of space exploration: targeted and nontargeted oxidative injury by high-charge and high-energy particles.

Authors:  Min Li; Géraldine Gonon; Manuela Buonanno; Narongchai Autsavapromporn; Sonia M de Toledo; Debkumar Pain; Edouard I Azzam
Journal:  Antioxid Redox Signal       Date:  2013-12-06       Impact factor: 8.401

Review 9.  Stereotactic body radiotherapy for oligo-recurrence within the nodal area from colorectal cancer.

Authors:  Young Seok Seo; Mi-Sook Kim; Hyung-Jun Yoo; Won-Il Jang
Journal:  World J Gastroenterol       Date:  2014-02-28       Impact factor: 5.742

Review 10.  Oxidative DNA damage caused by inflammation may link to stress-induced non-targeted effects.

Authors:  Carl N Sprung; Alesia Ivashkevich; Helen B Forrester; Christophe E Redon; Alexandros Georgakilas; Olga A Martin
Journal:  Cancer Lett       Date:  2013-09-14       Impact factor: 8.679

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