Literature DB >> 982058

Nitrous oxide "analgesia": resemblance to opiate action.

B A Berkowitz, S H Ngai, A D Finck.   

Abstract

Nitrous oxide produced a dose-related "analgesia" in mice (median effective dose, 55 percent). The analgesia was evaluated by means of a phenylquinone writhing test. Narcotic antagonists or chronic morphinization reduced nitrous oxide analgesia. Either nitrous oxide releases an endogenous analgesic or narcotic antagonists have analgesic antagonist properties heretofore unappreciated.

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Year:  1976        PMID: 982058     DOI: 10.1126/science.982058

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  33 in total

Review 1.  Nitrous oxide.

Authors:  J T Jastak; D Donaldson
Journal:  Anesth Prog       Date:  1991 Jul-Oct

2.  The trigeminal nuclei and selective analgesic drugs.

Authors:  K M Hargreaves
Journal:  Anesth Prog       Date:  1981-05

Review 3.  Arbiters of endogenous opioid analgesia: role of CNS estrogenic and glutamatergic systems.

Authors:  Alan R Gintzler; Nai-Jiang Liu
Journal:  Transl Res       Date:  2021-02-07       Impact factor: 7.012

4.  Macro- and microvascular effects of nitrous oxide in the rat.

Authors:  J L Matheny; K A Westphal; D R Richardson; G I Roth
Journal:  Anesth Prog       Date:  1991 Mar-Apr

5.  The effects of idazoxan combined with 30% nitrous oxide on the jaw-opening reflex in the rat.

Authors:  O Nakanishi; T Ishikawa; T Hirakawa; K Hattori; M Nishi
Journal:  Anesth Prog       Date:  1997

6.  Differential effects of isoflurane, halothane, and ketamine on the regional methionine-enkephalinlike immunoreactivity in the mouse brain.

Authors:  Junko Nogaya; Hisao Komatsu; Kenji Ogli
Journal:  J Anesth       Date:  1994-06       Impact factor: 2.078

7.  Prospective, double-blind, randomized trial of equimolar mixture of nitrous oxide/oxygen to prevent pain induced by insertion of venous access ports in cancer patients.

Authors:  Marie Cécile Douard; Mario di Palma; Patricia d'Agostino; Sylvie Chevret; Irène Kriegel; Bruno Falissard; Patrick Thierry; Brigitte George; Laurence Bussières; Jean-Louis Misset
Journal:  Support Care Cancer       Date:  2005-08-11       Impact factor: 3.603

8.  The effect of naloxone and morphine on convulsions in mice following withdrawal from nitrous oxide.

Authors:  H J Manson; G Dyke; J Melling; M Gough
Journal:  Can Anaesth Soc J       Date:  1983-01

9.  Differential epileptogenic potentials of selective mu and delta opiate receptor agonists.

Authors:  J Haffmans; M R Dzoljic
Journal:  J Neural Transm       Date:  1983       Impact factor: 3.575

10.  Physical dependence on nitrous oxide in mice: resemblance to alcohol but not to opiate withdrawal.

Authors:  B Milne; F W Cervenko; K H Jhamandas
Journal:  Can Anaesth Soc J       Date:  1981-01
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