Literature DB >> 982041

Antiserum to brain gangliosides produces recurrent epileptiform activity.

S E Karpiak, L Graf, M M Rapport.   

Abstract

A single injection of 10 microliters of antiserum to total brain ganglioside onto (and into) the sensorimotor cortex of the rat resulted in recurrent spiking in the cortical electroencephalogram, lasting from 7 to 17 days. Absorption of antibody with pure monosialoganglioside (GM1) completely abosished the effect. Spiking was reactivated after 4 weeks by intramuscular injection of pentylenetetrazole.

Entities:  

Mesh：

Substances：

Year:  1976        PMID： 982041     DOI： 10.1126/science.982041

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  14 in total

Review 1.  Neuropsychiatric lupus.

Authors:  J G Hanly
Journal:  Curr Rheumatol Rep       Date:  2001-06       Impact factor: 4.592

2.  Neuropsychiatric manifestations of systemic lupus erythematosus: the value of anticardiolipin, antigangliosides and antigalactocerebrosides antibodies.

Authors:  L T Costallat; R M de Oliveira; M B Santiago; W Cossermelli; A M Samara
Journal:  Clin Rheumatol       Date:  1990-12       Impact factor: 2.980

3.  A naturally occurring antibody in New Zealand mice cytotoxic to dissociated cerebellar cells.

Authors:  R J Harbeck; A A Hoffman; S A Hoffman; D W Shucard; R I Carr
Journal:  Clin Exp Immunol       Date:  1978-02       Impact factor: 4.330

4.  Central nervous system function in systemic lupus erythematosus.

Authors:  K Elkon; H Weissbach; N Brot
Journal:  Neurochem Res       Date:  1990-04       Impact factor: 3.996

Review 5.  Neuropsychiatric manifestations in systemic lupus erythematosus: epidemiology, pathophysiology and management.

Authors:  Mariana Postal; Lilian T L Costallat; Simone Appenzeller
Journal:  CNS Drugs       Date:  2011-09-01       Impact factor: 5.749

6.  The pathogenesis of neuropsychiatric lupus.

Authors:  J A Denburg; P Temesvari
Journal:  Can Med Assoc J       Date:  1983-02-01       Impact factor: 8.262

7.  Antiglycolipid autoantibody detected in the sera from systemic lupus erythematosus patients.

Authors:  T Hirano; H Hashimoto; Y Shiokawa; M Iwamori; Y Nagai; M Kasai; Y Ochiai; K Okumura
Journal:  J Clin Invest       Date:  1980-12       Impact factor: 14.808

8.  Neurocytotoxic antibodies in serum of patients with systemic lupus erythematosus.

Authors:  H G Bluestein
Journal:  Proc Natl Acad Sci U S A       Date:  1978-08       Impact factor: 11.205

9.  Ganglioside GM1, a molecular target for immunological and toxic attacks: similarity of neuropathological lesions induced by ganglioside-antiserum and cholera toxin.

Authors:  B Schwerer; H Lassmann; K Kitz; H Bernheimer
Journal:  Acta Neuropathol       Date:  1986       Impact factor: 17.088

Review 10.  The use of IVIG in neurological disease.

Authors:  A I Levinson
Journal:  Clin Rev Allergy       Date:  1992 Spring-Summer
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.