Literature DB >> 982032

Tail-pinch stimulation: sufficient motivation for learning.

G F Koob, P J Fray, S D Iversen.   

Abstract

A paper clip applied to the tails of rats induced gnawing and eating, which decreased in latency and increased in duration with experience. With sustained pressure to the tail, rats learned a new habit in order to gain access to wood chips on which to gnaw. That these are also properties of behavior elicited by electrical brain stimulation suggests that both manipulations may act through the same mechanism. These results support the hypothesis that a nonspecific arousing stimulus can be a sufficient condition for establishing learned habits.

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Year:  1976        PMID: 982032     DOI: 10.1126/science.982032

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  3 in total

Review 1.  The neural rejuvenation hypothesis of cocaine addiction.

Authors:  Yan Dong; Eric J Nestler
Journal:  Trends Pharmacol Sci       Date:  2014-06-20       Impact factor: 14.819

Review 2.  Alcohol dependence as a chronic pain disorder.

Authors:  Mark Egli; George F Koob; Scott Edwards
Journal:  Neurosci Biobehav Rev       Date:  2012-09-11       Impact factor: 8.989

3.  The effects of chronic chlordiazepoxide administration on ingestion of edible and nonedible substances by rats.

Authors:  A Posadas-Andrews; J Nieto
Journal:  Psychopharmacology (Berl)       Date:  1988       Impact factor: 4.530

  3 in total

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