Literature DB >> 9819867

Cervical length at 23 weeks of gestation: relation to demographic characteristics and previous obstetric history.

V C Heath1, T R Southall, A P Souka, A Novakov, K H Nicolaides.   

Abstract

OBJECTIVES: To examine the feasibility of introducing routine measurement of cervical length at 23 weeks of gestation, to establish the distribution of cervical lengths in a routine population of singleton pregnancies and to examine the relation between cervical length and demographic characteristics and previous obstetric history.
METHODS: Cervical length was measured by transvaginal sonography at 23 weeks of gestation in women with singleton pregnancies attending for routine antenatal care. The distribution of cervical lengths was established and the significance of differences in median cervical length between subgroups according to maternal age, ethnic origin, maternal ponderal index, cigarette smoking, alcohol drinking, drug abuse and previous obstetric history was calculated. In addition, 100 women were asked to complete a questionnaire aimed to assess the degree of discomfort, pain or embarrassment caused by the scan. In 100 pregnancies, cervical length was measured in each patient by two of four operators to determine intraobserver and interobserver variabilities.
RESULTS: During the study period, 2702 (80%) of the 3358 women attending for a 23-week scan agreed to participate in the study and, in all cases, the cervical length was measured successfully. The median cervical length was 38 mm and in 1.6% of cases the length was 15 mm or less. More than 90% of the women reported that the procedure was associated with no or only mild discomfort and embarrassment, whilst 85% found the ultrasound scan to be equally or less uncomfortable than a speculum examination. Measurement of cervical length was highly reproducible and, on 95% of occasions, the difference between two measurements by the same observer and by two observers was < or = 3.5 mm and < or = 4.2 mm, respectively. Cervical length was significantly shorter in women of Afro-Caribbean origin compared to Caucasians, those aged less than 20 years, those with a low ponderal index, those with a history of previous miscarriage or preterm delivery and in drug abusers.
CONCLUSIONS: Transvaginal sonographic measurement of cervical length is highly reproducible and it is associated with a minimal degree of discomfort to the patients. At 23 weeks, the median cervical length is 38 mm and, in 1.6% of the population, the length is 15 mm or less. There is an association between cervical length and demographic characteristics and previous obstetric history.

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Year:  1998        PMID: 9819867     DOI: 10.1046/j.1469-0705.1998.12050304.x

Source DB:  PubMed          Journal:  Ultrasound Obstet Gynecol        ISSN: 0960-7692            Impact factor:   7.299


  20 in total

1.  Clinical significance of early (< 20 weeks) vs. late (20-24 weeks) detection of sonographic short cervix in asymptomatic women in the mid-trimester.

Authors:  E Vaisbuch; R Romero; O Erez; J P Kusanovic; S Mazaki-Tovi; F Gotsch; V Romero; C Ward; T Chaiworapongsa; P Mittal; Y Sorokin; S S Hassan
Journal:  Ultrasound Obstet Gynecol       Date:  2010-10       Impact factor: 7.299

2.  Transabdominal evaluation of uterine cervical length during pregnancy fails to identify a substantial number of women with a short cervix.

Authors:  Edgar Hernandez-Andrade; Roberto Romero; Hyunyoung Ahn; Youssef Hussein; Lami Yeo; Steven J Korzeniewski; Tinnakorn Chaiworapongsa; Sonia S Hassan
Journal:  J Matern Fetal Neonatal Med       Date:  2012-03-16

3.  Management of pregnancies with cervical shortening: a very short cervix is a very big problem.

Authors:  Hee Joong Lee; Tae Chul Park; Errol R Norwitz
Journal:  Rev Obstet Gynecol       Date:  2009

4.  The risk of impending preterm delivery in asymptomatic patients with a nonmeasurable cervical length in the second trimester.

Authors:  Edi Vaisbuch; Roberto Romero; Shali Mazaki-Tovi; Offer Erez; Juan Pedro Kusanovic; Pooja Mittal; Francesca Gotsch; Clara Ward; Vivian Romero; Tinnakorn Chaiworapongsa; Percy Pacora; Lami Yeo; Sonia S Hassan
Journal:  Am J Obstet Gynecol       Date:  2010-07-24       Impact factor: 8.661

Review 5.  A blueprint for the prevention of preterm birth: vaginal progesterone in women with a short cervix.

Authors:  Roberto Romero; Lami Yeo; Jezid Miranda; Sonia S Hassan; Agustin Conde-Agudelo; Tinnakorn Chaiworapongsa
Journal:  J Perinat Med       Date:  2013-01       Impact factor: 1.901

6.  A sonographic short cervix as the only clinical manifestation of intra-amniotic infection.

Authors:  Sonia Hassan; Roberto Romero; Israel Hendler; Ricardo Gomez; Nahla Khalek; Jimmy Espinoza; Jyh Kae Nien; Stanley M Berry; Emmanuel Bujold; Natalia Camacho; Yoram Sorokin
Journal:  J Perinat Med       Date:  2006       Impact factor: 1.901

Review 7.  Precocious cervical ripening as a screening target to predict spontaneous preterm delivery among asymptomatic singleton pregnancies: a systematic review.

Authors:  Qing Li; Mathew Reeves; John Owen; Louis G Keith
Journal:  Am J Obstet Gynecol       Date:  2014-07-11       Impact factor: 8.661

Review 8.  Additional effects of the cervical length measurement in women with preterm contractions: a systematic review.

Authors:  Jolande Y Vis; Rosanna A Kuin; William A Grobman; Ben Willem J Mol; Patrick M M Bossuyt; Brent C Opmeer
Journal:  Arch Gynecol Obstet       Date:  2011-04-12       Impact factor: 2.344

9.  Vaginal progesterone in risk reduction of preterm birth in women with short cervix in the midtrimester of pregnancy.

Authors:  Meena Khandelwal
Journal:  Int J Womens Health       Date:  2012-09-14

10.  The effect of polyhydramnios on cervical length in twins: a controlled intervention study in complicated monochorionic pregnancies.

Authors:  Neelam Engineer; Keelin O'Donoghue; Ruwan C Wimalasundera; Nicholas M Fisk
Journal:  PLoS One       Date:  2008-12-02       Impact factor: 3.240

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