Literature DB >> 9818814

Management of substernal goiter.

J L Netterville1, S C Coleman, J C Smith, M M Smith, T A Day, B B Burkey.   

Abstract

OBJECTIVE: To analyze the presentation, evaluation and treatment of patients with large substernal goiters, with emphasis on the radiographic evaluation and the results of treatment. STUDY
DESIGN: A retrospective chart review of 150 patients undergoing thyroidectomy at the Vanderbilt University Department of Otolaryngology-Head and Neck Surgery.
METHODS: Charts of patients undergoing thyroidectomy were reviewed. Those with substernal goiter, defined as a major portion of the goiter within the mediastinum, were included in the study. When available, the radiographic studies were reviewed by a staff neuroradiologist.
RESULTS: Twenty-three patients (15.3%) presented with substernal extension of the goiter. Characteristics of these patients included mean age of 59 years, 78% female, symptoms of compression such as dyspnea, choking, and dysphagia (65%), hoarseness (43%), and previous thyroid surgery (30%). Seventeen percent were asymptomatic. Preoperative radiographs demonstrated tracheal compression (73%), tracheal deviation (77%), esophageal compression (27%), and major vessel displacement (50%). Histology revealed multinodular goiter (16/23, 70%), thyroiditis (3/23, 13%), and malignancy (4/23, 17%). The average size of the resected specimen in greatest dimension was 8.0 cm (range, 3.0-14.0 cm) and weighed 148 g (range, 39-426 g). All were successfully approached through a transcervical incision without the need for sternotomy, and total thyroidectomy was performed in 83% of the cases. No major complications have been documented, and no evidence of tracheomalacia was encountered.
CONCLUSION: Despite the large size of these goiters and the significant involvement of the major mediastinal structures, all were approached through the transcervical incision. Further, despite significant tracheal involvement, there were no cases of tracheomalacia or major complications. For intraoperative planning, the authors advocate the routine use of preoperative computed tomography scanning.

Entities:  

Mesh:

Year:  1998        PMID: 9818814     DOI: 10.1097/00005537-199811000-00005

Source DB:  PubMed          Journal:  Laryngoscope        ISSN: 0023-852X            Impact factor:   3.325


  31 in total

Review 1.  Treatment of multinodular goiter by surgery.

Authors:  L J DeGroot
Journal:  J Endocrinol Invest       Date:  2001-11       Impact factor: 4.256

Review 2.  Overview of the management of differentiated thyroid cancer.

Authors:  Jyotika K Fernandes; Terry A Day; Mary S Richardson; Anand K Sharma
Journal:  Curr Treat Options Oncol       Date:  2005-01

3.  Management of intrathoracic goitre.

Authors:  Pia Pace-Asciak; Kevin Higgins
Journal:  Can J Surg       Date:  2008-10       Impact factor: 2.089

4.  Limited upper sternotomy in general thoracic surgery.

Authors:  Marco Alifano; Sergio N Forti Parri; Walid Abu Arab; Barbara Bonfanti; Nicola Lacava; Calogero Porrello; Maurizio Boaron
Journal:  Surg Today       Date:  2008-03-27       Impact factor: 2.549

5.  Sternotomy for substernal goiter: retrospective study of 52 operations.

Authors:  Lars Rolighed; Hanne Rønning; Peer Christiansen
Journal:  Langenbecks Arch Surg       Date:  2015-02-19       Impact factor: 3.445

6.  EXPERIENCE WITH MANAGING RETROSTERNAL GOITRES IN IBADAN, NIGERIA.

Authors:  O O Ayandipo; A O Afolabi; O O Afuwape; B E Bolaji; M A Salami
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7.  Medial Approach for the Resection of Goiters with Suprahyoid, Retropharyngeal, or Substernal Extension.

Authors:  Harry H Ching; Jacob B Kahane; Megan J Foggia; Annabel E Barber; Robert C Wang
Journal:  World J Surg       Date:  2018-05       Impact factor: 3.352

8.  Does nodule size predict compressive symptoms in patients with thyroid nodules?

Authors:  Oliver S Eng; Lindsay Potdevin; Tomer Davidov; Shou-En Lu; Chunxia Chen; Stanley Z Trooskin
Journal:  Gland Surg       Date:  2014-11

Review 9.  Diagnosis and management of substernal goiter at the University of Crete.

Authors:  John Bizakis; Alexandros Karatzanis; Jiannis Hajiioannou; Constantinos Bourolias; Eleutherios Maganas; Elias Spanakis; Argyro Bizaki; George Velegrakis
Journal:  Surg Today       Date:  2008-02-01       Impact factor: 2.549

10.  Surgical management of mediastinal goiter: risk factors for sternotomy.

Authors:  Stanisław Cichoń; Ryszard Anielski; Aleksander Konturek; Marcin Baczyński; Wojciech Cichoń; Paweł Orlicki
Journal:  Langenbecks Arch Surg       Date:  2008-05-17       Impact factor: 3.445

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