| Literature DB >> 981709 |
T B Cooper, D Allen, G M Simpson.
Abstract
A highly sensitive and reproducible GLC technique for the quantitation of amitriptyline and nortriptyline is described. The lower limit of detection is less than 1 ng/ml. 5 ng/ml samples (3 ml aliquots) can be accurately quantified (C of V less than 5%). Steady state data are reported together with data on amitriptyline and nortriptyline levels obtained in a volunteer who ingested a single oral dose (25 mg) of amitriptyline (Elavil).Entities:
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Year: 1976 PMID： 981709
Source DB: PubMed Journal: Psychopharmacol Commun ISSN： 0098-616X