Y H Shi1. 1. Fourth Affiliated Hospital of Hebei Medical College, Shijiazhuang.
Abstract
OBJECTIVE: To observe the effect of Composite Dansen Droplet Pills (CDDP) in treating chronic stable angina. METHODS: The effect of oral CDDP and Sordi were compared with those of placebo in 64 patients with chronic stable angina. Patients performed symptom limited multistage, supine bicycle ergometric exercise, while undergoing non-imaging radionuclide angiocardiographic examination after 8 week periods treatment of 10-15 pills, three times daily, 10-15 mg Sordi three times daily, and placebo. All drugs were given double blind and randomly. Adverse effects that occurred during drug treatment were minor and generally well tolerated. RESULTS:CDDP not only appeared to be more effective than Sordi in increasing exercise duration and delaying time of onset of exercise angina or peak effort, but also seems to be superior to Sordi in improving either the stress-induced myocardial ischemia or the exercise left ventricular systolic function. CONCLUSION:CDDP is a more effective drug in treating chronic stable angina.
RCT Entities:
OBJECTIVE: To observe the effect of Composite Dansen Droplet Pills (CDDP) in treating chronic stable angina. METHODS: The effect of oral CDDP and Sordi were compared with those of placebo in 64 patients with chronic stable angina. Patients performed symptom limited multistage, supine bicycle ergometric exercise, while undergoing non-imaging radionuclide angiocardiographic examination after 8 week periods treatment of 10-15 pills, three times daily, 10-15 mg Sordi three times daily, and placebo. All drugs were given double blind and randomly. Adverse effects that occurred during drug treatment were minor and generally well tolerated. RESULTS:CDDP not only appeared to be more effective than Sordi in increasing exercise duration and delaying time of onset of exercise angina or peak effort, but also seems to be superior to Sordi in improving either the stress-induced myocardial ischemia or the exercise left ventricular systolic function. CONCLUSION:CDDP is a more effective drug in treating chronic stable angina.
Authors: Wei Huiping; Wang Yu; Jin Pei; Li Jiao; Zhang Shian; Jiang Hugang; Wang Zheng; Li Yingdong Journal: Medicine (Baltimore) Date: 2019-03 Impact factor: 1.889