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Literature DB >> 9812373

Saccharomyces cerevisiae ACR2 gene encodes an arsenate reductase.

Abstract

The ACR2 gene of Saccharomyces cerevisiae was disrupted by insertion of a HIS3 gene. Cells with the disruption were sensitive to arsenate. This phenotype could be complemented by ACR2 on a plasmid. The ACR2 gene was cloned and expressed in Escherichia coli as a malE gene fusion with a C-terminal histidine tag. The combination of chimeric MBP-Acr2-6H protein and yeast cytosol from an ACR2-disrupted strain exhibited arsenate reductase activity.

Entities: Chemical Gene Species

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Year: 1998 PMID： 9812373 DOI： 10.1111/j.1574-6968.1998.tb13265.x

Source DB: PubMed Journal: FEMS Microbiol Lett ISSN： 0378-1097 Impact factor: 2.742

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Cited

29 in total

1. Pathways of As(III) detoxification in Saccharomyces cerevisiae.

Authors: M Ghosh; J Shen; B P Rosen
Journal: Proc Natl Acad Sci U S A Date: 1999-04-27 Impact factor: 11.205

2. All intermediates of the arsenate reductase mechanism, including an intramolecular dynamic disulfide cascade.

Authors: Joris Messens; José C Martins; Karolien Van Belle; Elke Brosens; Aline Desmyter; Marjan De Gieter; Jean-Michel Wieruszeski; Rudolph Willem; Lode Wyns; Ingrid Zegers
Journal: Proc Natl Acad Sci U S A Date: 2002-06-18 Impact factor: 11.205

3. Relief of arsenate toxicity by Cd-stimulated phytochelatin synthesis in the green alga Chlamydomonas reinhardtii.

Authors: Isao Kobayashi; Shoko Fujiwara; Hirotaka Saegusa; Masahiro Inouhe; Hiroko Matsumoto; Mikio Tsuzuki
Journal: Mar Biotechnol (NY) Date: 2006-01-01 Impact factor: 3.619

4. Hyperaccumulation of arsenic in the shoots of Arabidopsis silenced for arsenate reductase (ACR2).

Authors: Om Parkash Dhankher; Barry P Rosen; Elizabeth C McKinney; Richard B Meagher
Journal: Proc Natl Acad Sci U S A Date: 2006-03-27 Impact factor: 11.205

5. Molecular characterization of Alr1105 a novel arsenate reductase of the diazotrophic cyanobacterium Anabaena sp. PCC7120 and decoding its role in abiotic stress management in Escherichia coli.

Authors: Sarita Pandey; Alok K Shrivastava; Rashmi Rai; Lal Chand Rai
Journal: Plant Mol Biol Date: 2013-07-09 Impact factor: 4.076

Saccharomyces cerevisiae ACR2 gene encodes an arsenate reductase.

1. Pathways of As(III) detoxification in Saccharomyces cerevisiae.

2. All intermediates of the arsenate reductase mechanism, including an intramolecular dynamic disulfide cascade.

3. Relief of arsenate toxicity by Cd-stimulated phytochelatin synthesis in the green alga Chlamydomonas reinhardtii.

4. Hyperaccumulation of arsenic in the shoots of Arabidopsis silenced for arsenate reductase (ACR2).

5. Molecular characterization of Alr1105 a novel arsenate reductase of the diazotrophic cyanobacterium Anabaena sp. PCC7120 and decoding its role in abiotic stress management in Escherichia coli.

6. Adventitious arsenate reductase activity of the catalytic domain of the human Cdc25B and Cdc25C phosphatases.

7. The effect of hybridization on transposable element accumulation in an undomesticated fungal species.

8. Arsenate reductase, mycothiol, and mycoredoxin concert thiol/disulfide exchange.

9. Pathways of arsenic uptake and efflux.

10. Arsenic sensing and resistance system in the cyanobacterium Synechocystis sp. strain PCC 6803.