Literature DB >> 9811188

Acute hemolytic crisis with fulminant hepatic failure as the first manifestation of Wilson's disease: a case report.

J J Lee1, H J Kim, I J Chung, H Kook, J R Byun, S Y Kwon, M R Park, K S Choi, T J Hwang, D W Ryang.   

Abstract

We report a 27-year-old woman who developed Coombs' negative hemolytic anemia and fulminant hepatic failure as the initial manifestation of Wilson's disease. Unmeasurably low level of serum alkaline phosphatase provided a clue to the diagnosis of Wilson's disease. The diagnosis was established with the presence of Kayser-Fleischer ring, decreased serum ceruloplasmin level, and elevated urine and serum copper levels. In spite of repeated plasmapheresis, she died of multiorgan failure on the fifth hospital day.

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Year:  1998        PMID： 9811188      PMCID： PMC3054522          DOI： 10.3346/jkms.1998.13.5.548

Source DB:  PubMed          Journal:  J Korean Med Sci        ISSN： 1011-8934            Impact factor:   2.153


  3 in total

1.  Screening for Wilson disease in acute liver failure: a comparison of currently available diagnostic tests.

Authors:  Jessica D Korman; Irene Volenberg; Jody Balko; Joe Webster; Frank V Schiodt; Robert H Squires; Robert J Fontana; William M Lee; Michael L Schilsky
Journal:  Hepatology       Date:  2008-10       Impact factor: 17.425

2.  Analysis of the T1288R mutation of the Wilson disease ATP7B gene in four generations of a family: possible genotype-phenotype correlation with hepatic onset.

Authors:  Lorenzo Leggio; Noemi Malandrino; Georgios Loudianos; Ludovico Abenavoli; Maria Barbara Lepori; Esmeralda Capristo; Stefano De Virgiliis; Giovanni Gasbarrini; Giovanni Addolorato
Journal:  Dig Dis Sci       Date:  2007-04-05       Impact factor: 3.199

3.  Biomarkers for diagnosis of Wilson's disease.

Authors:  Aidan Ryan; Sarah J Nevitt; Orla Tuohy; Paul Cook
Journal:  Cochrane Database Syst Rev       Date:  2019-11-19
  3 in total

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