Graduate education in microscopic anatomy.

One of the most striking changes to affect the direction of current biomedical research is the increasing use of transgenic or gene-targeted mice as models of gene function and human disease. The proliferation of transgenic and gene-targeting technology has contributed to a rebirth of histology as an important research tool and is driving the need for broadly trained investigators with expertise at both the molecular and organismal levels. Since the ultimate goal of graduate-student education is the training of the next generation of independent scientists, it is important that graduate training programs provide students with the background required to take advantage of the unique resources provided by these mouse models. Anatomists are well suited to provide such training by incorporating mouse anatomy, physiology, and genetics into traditional coursework in microscopic anatomy.