| Literature DB >> 9810278 |
N P Lopes, P Chicaro, M J Kato, S Albuquerque, M Yoshida.
Abstract
Dichloromethane extracts from twigs of Virola surinamensis (Myristicaceae) showed in vitro trypanosomicidal activity against trypomastigote form of Trypanosoma cruzi. The extract, fractionated by preparative circular chromatography and preparative high-performance liquid chromatography yielded two steroids, two lignans, five flavonoids, and one polyketide. Among the isolated compounds, the lignans presented the highest trypanosomicidal activity.Entities:
Mesh:
Substances:
Year: 1998 PMID: 9810278 DOI: 10.1055/s-2006-957548
Source DB: PubMed Journal: Planta Med ISSN: 0032-0943 Impact factor: 3.352