Literature DB >> 9810268

Tribulusamide A and B, new hepatoprotective lignanamides from the fruits of Tribulus terrestris: indications of cytoprotective activity in murine hepatocyte culture.

J X Li1, Q Shi, Q B Xiong, J K Prasain, Y Tezuka, T Hareyama, Z T Wang, K Tanaka, T Namba, S Kadota.   

Abstract

Tribulusamides A (1) and B (2), new lignanamides embracing two cinnamic amide parts joined in a cis configuration, were isolated from the fruits of Tribulus terrestris, together with four known compounds, N-trans-feruloyltyramine (3), terrestriamide (4), N-trans-coumaroyltyramine (5), and beta-sitosterol. The structures were elucidated by 2D-NMR spectroscopy. Addition of compounds 1-5, especially 1 and 2, to primary cultured mouse hepatocytes significantly prevented cell death induced by D-galactosamine (D-GalN)/tumor necrosis factor alpha (TNF-alpha).

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Year:  1998        PMID: 9810268     DOI: 10.1055/s-2006-957535

Source DB:  PubMed          Journal:  Planta Med        ISSN: 0032-0943            Impact factor:   3.352


  7 in total

1.  Protective Effect of Ethanol Extract of Gymnosporia montana (Roth) Bemth. in Paracetamol-induced Hepatotoxicity in Rats.

Authors:  Parvati B Patel; T K Patel; P Shah; Seema N Baxi; H O Sharma; C B Tripathi
Journal:  Indian J Pharm Sci       Date:  2010-05       Impact factor: 0.975

Review 2.  A review of hepatoprotective plants used in saudi traditional medicine.

Authors:  Abdulrahman K Al-Asmari; Abdulrahman M Al-Elaiwi; Md Tanwir Athar; Mohammad Tariq; Ahmed Al Eid; Saeed M Al-Asmary
Journal:  Evid Based Complement Alternat Med       Date:  2014-12-18       Impact factor: 2.629

3.  Comparative Physicochemical Evaluation of Kharekhasak (Tribulus terrestris Linn.) Before and After Mudabbar Process.

Authors:  Abdullah Tauheed; Salma Khanam; Mohd Akhtar Ali; Mohammad Zaigham
Journal:  Pharmacognosy Res       Date:  2017 Oct-Dec

Review 4.  A Comprehensive Review of the Phytochemical, Pharmacological, and Toxicological Properties of Tribulus terrestris L.

Authors:  Ruxandra Ștefănescu; Amelia Tero-Vescan; Ancuța Negroiu; Elena Aurică; Camil-Eugen Vari
Journal:  Biomolecules       Date:  2020-05-12

5.  Discovery of Active Ingredients Targeted TREM2 by SPR Biosensor-UPLC/MS Recognition System, and Investigating the Mechanism of Anti-Neuroinflammatory Activity on the Lignin-Amides from Datura metel Seeds.

Authors:  Si-Yi Wang; Yan Liu; Xiao-Mao Li; Adnan Mohammed Algradi; Hai Jiang; Yan-Ping Sun; Wei Guan; Juan Pan; Hai-Xue Kuang; Bing-You Yang
Journal:  Molecules       Date:  2021-09-30       Impact factor: 4.411

6.  Effects of the Fruit Extract of Tribulus terrestris on Skin Inflammation in Mice with Oxazolone-Induced Atopic Dermatitis through Regulation of Calcium Channels, Orai-1 and TRPV3, and Mast Cell Activation.

Authors:  Seok Yong Kang; Hyo Won Jung; Joo Hyun Nam; Woo Kyung Kim; Jong-Seong Kang; Young-Ho Kim; Cheong-Weon Cho; Chong Woon Cho; Yong-Ki Park; Hyo Sang Bae
Journal:  Evid Based Complement Alternat Med       Date:  2017-11-14       Impact factor: 2.629

7.  Molecular mechanism of apoptosis induction in Jurkat E6-1 cells by Tribulus terrestris alkaloids extract.

Authors:  Shriniwas S Basaiyye; Pravin K Naoghare; Sanjeev Kanojiya; Amit Bafana; Patrizio Arrigo; Kannan Krishnamurthi; Saravanadevi Sivanesan
Journal:  J Tradit Complement Med       Date:  2017-12-14
  7 in total

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