Literature DB >> 9810228

DNA end-joining: from yeast to man.

S E Critchlow1, S P Jackson.   

Abstract

DNA non-homologous end-joining (NHEJ) is a crucial process that has been conserved highly throughout eukaryotic evolution. At its heart is a multiprotein complex containing the KU70-KU80 heterodimer. Recent work has identified additional proteins involved in this pathway, providing insights into the mechanism of NHEJ and revealing exciting links with the control of transcription, telomere length and chromatin structure.

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Year:  1998        PMID： 9810228     DOI： 10.1016/s0968-0004(98)01284-5

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  170 in total

1.  Multiple heterologies increase mitotic double-strand break-induced allelic gene conversion tract lengths in yeast.

Authors:  J A Nickoloff; D B Sweetser; J A Clikeman; G J Khalsa; S L Wheeler
Journal:  Genetics       Date:  1999-10       Impact factor: 4.562

2.  Purification and DNA binding properties of the ataxia-telangiectasia gene product ATM.

Authors:  G C Smith; R B Cary; N D Lakin; B C Hann; S H Teo; D J Chen; S P Jackson
Journal:  Proc Natl Acad Sci U S A       Date:  1999-09-28       Impact factor: 11.205

Review 3.  Links between replication, recombination and genome instability in eukaryotes.

Authors:  H Flores-Rozas; R D Kolodner
Journal:  Trends Biochem Sci       Date:  2000-04       Impact factor: 13.807

4.  Homologous and non-homologous recombination differentially affect DNA damage repair in mice.

Authors:  J Essers; H van Steeg; J de Wit; S M Swagemakers; M Vermeij; J H Hoeijmakers; R Kanaar
Journal:  EMBO J       Date:  2000-04-03       Impact factor: 11.598

5.  A mechanistic basis for Mre11-directed DNA joining at microhomologies.

Authors:  T T Paull; M Gellert
Journal:  Proc Natl Acad Sci U S A       Date:  2000-06-06       Impact factor: 11.205

6.  DNA damage-dependent nuclear dynamics of the Mre11 complex.

Authors:  O K Mirzoeva; J H Petrini
Journal:  Mol Cell Biol       Date:  2001-01       Impact factor: 4.272

7.  DNA double-strand break repair in cell-free extracts from Ku80-deficient cells: implications for Ku serving as an alignment factor in non-homologous DNA end joining.

Authors:  E Feldmann; V Schmiemann; W Goedecke; S Reichenberger; P Pfeiffer
Journal:  Nucleic Acids Res       Date:  2000-07-01       Impact factor: 16.971

Review 8.  Manipulating the mammalian genome by homologous recombination.

Authors:  K M Vasquez; K Marburger; Z Intody; J H Wilson
Journal:  Proc Natl Acad Sci U S A       Date:  2001-07-17       Impact factor: 11.205

9.  Dicentric chromosome stretching during anaphase reveals roles of Sir2/Ku in chromatin compaction in budding yeast.

Authors:  D A Thrower; K Bloom
Journal:  Mol Biol Cell       Date:  2001-09       Impact factor: 4.138

10.  Characterization of retrovirus-host DNA junctions in cells deficient in nonhomologous-end joining.

Authors:  K Taganov; R Daniel; R A Katz; O Favorova; A M Skalka
Journal:  J Virol       Date:  2001-10       Impact factor: 5.103
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