Literature DB >> 9808907

Human leucocytic antigens (HLA) in breast cancer.

B M Biswal1, R Kumar, P K Julka, U Sharma, M C Vaidya.   

Abstract

HLA frequencies of fifty (50) female breast cancer patients were compared with 200 age matched female controls. A total of 20 HLA-A locus, 35 HLA-B locus and 8 HLA-C locus antigens were studied. The HLA-A2, A11, Aw19 and A30; HLA-B8, B14 and HLA Cw6 were found significantly higher than the controls. The HLA-A11, HLA-Aw19 and HLA-B8 were found protective whereas, HLA-A2, HLA-B14 and HLA-Cw6 were a risk for breast cancer. The prective antigens' probable involvement through immunogenic mechanism in breast cancer is emphasized in this article.

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Year:  1998        PMID: 9808907

Source DB:  PubMed          Journal:  Indian J Med Sci        ISSN: 0019-5359


  4 in total

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Journal:  Med Oncol       Date:  2010-01-13       Impact factor: 3.064

4.  Structure of tumor necrosis factor-alpha haploblocks in European populations.

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  4 in total

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