Literature DB >> 9808503

Mycophenolate mofetil-induced villous atrophy.

D Ducloux1, Y Ottignon, S Semhoun-Ducloux, S Labbé, Y Saint-Hillier, J P Miguet, P Carayon, J M Chalopin.   

Abstract

Mycophenolate mofetil (MMF) is a new immunosuppressant developed for the prevention and treatment of acute renal rejection after transplantation. Diarrhea is the most frequent side effect observed during treatment with MMF. Its pathogenic mechanisms remain unknown. We describe a case of severe diarrhea due to villous atrophy in a renal transplant recipient during treatment with MMF. The patient was free of symptoms before MMF. Villous atrophy disappeared a few months after MMF withdrawal.

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Year:  1998        PMID： 9808503     DOI： 10.1097/00007890-199810270-00027

Source DB:  PubMed          Journal:  Transplantation        ISSN： 0041-1337            Impact factor:   4.939


  20 in total

1.  Inosine 5'-monophosphate dehydrogenase 1 haplotypes and association with mycophenolate mofetil gastrointestinal intolerance in pediatric heart transplant patients.

Authors:  Erin L Ohmann; Gilbert J Burckart; Yan Chen; Vera Pravica; Maria M Brooks; Adriana Zeevi; Steven A Webber
Journal:  Pediatr Transplant       Date:  2010-11

2.  The occurrence of diarrhea not related to the pharmacokinetics of MPA and its metabolites in liver transplant patients.

Authors:  Zhang Wei Xia; Chen Yong Jun; Chen Hao; Chen Bing; Shi Min Min; Xie Jun Jie
Journal:  Eur J Clin Pharmacol       Date:  2010-05-15       Impact factor: 2.953

Review 3.  The influence of pharmacogenetics and cofactors on clinical outcomes in kidney transplantation.

Authors:  Nicolas Picard; Pierre Marquet
Journal:  Expert Opin Drug Metab Toxicol       Date:  2011-03-25       Impact factor: 4.481

4.  Diarrhea in a Long-Term Kidney-Pancreas Recipient.

Authors:  Margaret J Bia
Journal:  Clin J Am Soc Nephrol       Date:  2017-03-24       Impact factor: 8.237

5.  Sprue-Like Enteropathy Associated With Oxcarbazepine.

Authors:  Pedro Luis González-Cordero; Nuria Fernandez-Gonzalez; Javier Molina-Infante
Journal:  Am J Gastroenterol       Date:  2016-11       Impact factor: 10.864

6.  Collagenous colitis-like condition in immunosuppressed infant baboons.

Authors:  Eefje M Dons; Gabriel J Echeverri; Lora H Rigatti; Edwin Klein; Claudia Montoya; Roman F Wolf; Jan N M Ijzermans; David K C Cooper; Robert Wagner
Journal:  Inflamm Bowel Dis       Date:  2012-01-31       Impact factor: 5.325

Review 7.  Adverse gastrointestinal effects of mycophenolate mofetil: aetiology, incidence and management.

Authors:  M Behrend
Journal:  Drug Saf       Date:  2001       Impact factor: 5.606

Review 8.  Cytomegalovirus infection and abdominal pain with mycophenolate mofetil: is there a link?

Authors:  H Gallagher; P A Andrews
Journal:  Drug Saf       Date:  2001       Impact factor: 5.606

9.  Risk of diarrhoea in a long-term cohort of renal transplant patients given mycophenolate mofetil: the significant role of the UGT1A8 2 variant allele.

Authors:  Jean-Baptiste Woillard; Jean-Philippe Rerolle; Nicolas Picard; Annick Rousseau; Mireille Drouet; Eliza Munteanu; Marie Essig; Pierre Marquet; Yann Le Meur
Journal:  Br J Clin Pharmacol       Date:  2010-06       Impact factor: 4.335

10.  Steatorrhoea complicating post-infectious diarrhoea in a renal transplant patient on mycophenolate mofetil therapy.

Authors:  Senyo Tagboto; Farman Akhtar
Journal:  Clin Exp Nephrol       Date:  2008-12-10       Impact factor: 2.801
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