Literature DB >> 9803832

Chronic obstructive pulmonary disease: new opportunities for drug development.

P J Barnes1.   

Abstract

Chronic obstructive pulmonary disease (COPD) is common and there is an increasing worldwide prevalence. There are no available treatments to prevent the progression of airflow obstruction, but greater understanding of the molecular and cellular mechanisms involved in COPD has identified many new therapeutic targets, including inflammatory mediators, proteases and adhesion molecules. In this review, Peter Barnes considers potential new drugs for this neglected disease.

Entities:  

Mesh：

Substances：

Year:  1998        PMID： 9803832     DOI： 10.1016/s0165-6147(98)01245-0

Source DB:  PubMed          Journal:  Trends Pharmacol Sci        ISSN： 0165-6147            Impact factor:   14.819


  10 in total

Review 1.  Genetics and pulmonary medicine. 9. Molecular genetics of chronic obstructive pulmonary disease.

Authors:  P J Barnes
Journal:  Thorax       Date:  1999-03       Impact factor: 9.139

2.  Determining the functional role of TRPC channels in primary cells.

Authors:  Su Li; Martin Gosling; Chris Poll
Journal:  Pflugers Arch       Date:  2005-08-03       Impact factor: 3.657

3.  Airway reactivity, inflammatory cell influx and nitric oxide in guinea-pig airways after lipopolysaccharide inhalation.

Authors:  T J Toward; K J Broadley
Journal:  Br J Pharmacol       Date:  2000-09       Impact factor: 8.739

4.  Effect of the long-acting tachykinin NK(1) receptor antagonist MEN 11467 on tracheal mucus secretion in allergic ferrets.

Authors:  S Khan; Y C Liu; A M Khawaja; S Manzini; D F Rogers
Journal:  Br J Pharmacol       Date:  2001-01       Impact factor: 8.739

Review 5.  Phosphodiesterase 4 inhibitors and the treatment of asthma: where are we now and where do we go from here?

Authors:  M A Giembycz
Journal:  Drugs       Date:  2000-02       Impact factor: 9.546

6.  Anti-spasmogenic activity of isoenzyme-selective phosphodiesterase inhibitors in guinea-pig trachealis.

Authors:  M M Bernareggi; M G Belvisi; H Patel; P J Barnes; M A Giembycz
Journal:  Br J Pharmacol       Date:  1999-09       Impact factor: 8.739

Review 7.  The glucocorticoid receptor: a revisited target for toxins.

Authors:  Jeanette I Webster Marketon; Esther M Sternberg
Journal:  Toxins (Basel)       Date:  2010-06-09       Impact factor: 4.546

8.  Role of macrophage migration inhibitory factor (MIF) in allergic and endotoxin-induced airway inflammation in mice.

Authors:  M Korsgren; L Källström; L Uller; T Bjerke; F Sundler; C G Persson; O Korsgren
Journal:  Mediators Inflamm       Date:  2000       Impact factor: 4.711

Review 9.  Dynamics of airway response in lung microsections: a tool for studying airway-extra cellular matrix interactions.

Authors:  Mohammad Afzal Khan
Journal:  J Biomed Sci       Date:  2016-05-12       Impact factor: 8.410

Review 10.  Global Initiative for Chronic Obstructive Lung Disease strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease: an Asia-Pacific perspective.

Authors: 
Journal:  Respirology       Date:  2005-01       Impact factor: 6.424
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.