Literature DB >> 980371

Some examples of dose-response studies in chemical carcinogenesis.

R Port, D Schmähl, J Wahrendorf.   

Abstract

Three studies of DRUCKREY and his group, on diethylnitrosamine and 4-dimethylaminostilbene, are described. In a recent experiment, urethane was given chronically to rats and mice, at doses between 100 and 12,500 mug/kg/day. The results in rats were evaluated with the Mantel-Bryan procedure; risk estimates greatly differed, depending on the slope used for calculation.

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Year:  1976        PMID: 980371     DOI: 10.1159/000225107

Source DB:  PubMed          Journal:  Oncology        ISSN: 0030-2414            Impact factor:   2.935


  1 in total

1.  The problem of estimating safe dose levels in chemical carcinogenesis.

Authors:  J Wahrendorf
Journal:  J Cancer Res Clin Oncol       Date:  1979-10       Impact factor: 4.553

  1 in total

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