| Literature DB >> 9803586 |
F K Nkrumah1, M Osei-Kwasi, S K Dunyo, K A Koram, E A Afari.
Abstract
In a randomized controlled trial in a measles endemic area, standard-dose (4.0 log10pfu) AIK-C measles vaccine administered at 6 months of age was compared to standard-dose Schwarz vaccine (3.7log10pfu) given at 9 months. Seroconversion rates at 3 and 6 months after immunization in the two groups were comparable and similar. The geometric mean titres achieved were, however, significantly higher in the Schwarz group (P < 0.05). No immediate serious side-effects were observed with either vaccine. We conclude that standard-dose AIK-C measles vaccine can be recommended for measles immunization in children below 9 months of age, especially in highly endemic and high-risk areas in developing countries.Entities:
Keywords: Africa; Africa South Of The Sahara; Age Factors; Child Health Services; Comparative Studies; Delivery Of Health Care; Demographic Factors; Developing Countries; Diseases; English Speaking Africa; Ghana; Health; Health Services; Immunization; Infant; Maternal-child Health Services; Measles--prevention and control; Population; Population Characteristics; Primary Health Care; Research Methodology; Research Report; Studies; Vaccination; Vaccines--administraction and dosage; Viral Diseases; Western Africa; Youth
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Year: 1998 PMID： 9803586 PMCID： PMC2305762
Source DB: PubMed Journal: Bull World Health Organ ISSN： 0042-9686 Impact factor: 9.408