OBJECTIVE: This study was conducted to assess treatment results in patients undergoing functional endoscopic sinus surgery for chronic sinusitis, with evaluation of prognostic indicators of success and failure. METHOD: The study included 393 patients who underwent endoscopic sinus surgery for chronic sinusitis over a 4-year period. The diagnosis of chronic sinusitis was based on ongoing symptomatology for greater than 3 months and the presence of mucosal disease on computerized tomography (CT). A retrospective analysis was done looking at patient data, presenting symptoms, CT findings, operative reports, pathology reports, and outcome at 6- and 12-month follow-up. The prognostic significance of selected factors was evaluated using chi-square analysis. RESULTS: A positive history for asthma, allergy, and ASA triad was present in 29.5%, 34.6%, and 10.9% of patients, respectively. Previous sinus surgery was done in 31.9%, and 15.7% of patients were smokers. The most common presenting complaint was nasal congestion/obstruction, followed by facial pain/headaches and olfactory disturbance. A positive outcome was achieved in 80.5% of patients at 6 months and in 69.7% at 12-month follow-up. Revision surgery within a year was needed in 4.1% of patients. Factors affecting outcome included asthma, smoking, polyposis, previous surgery, and pansinusitis. CONCLUSIONS: Extent of disease, as reflected by polyposis, pansinusitis, and premorbid history, is the most important determinant of outcome. Concomitant changes in ciliary motility secondary to asthma or smoking further impede surgical outcome. Future studies focusing on the disease process of chronic sinusitis are needed.
OBJECTIVE: This study was conducted to assess treatment results in patients undergoing functional endoscopic sinus surgery for chronic sinusitis, with evaluation of prognostic indicators of success and failure. METHOD: The study included 393 patients who underwent endoscopic sinus surgery for chronic sinusitis over a 4-year period. The diagnosis of chronic sinusitis was based on ongoing symptomatology for greater than 3 months and the presence of mucosal disease on computerized tomography (CT). A retrospective analysis was done looking at patient data, presenting symptoms, CT findings, operative reports, pathology reports, and outcome at 6- and 12-month follow-up. The prognostic significance of selected factors was evaluated using chi-square analysis. RESULTS: A positive history for asthma, allergy, and ASA triad was present in 29.5%, 34.6%, and 10.9% of patients, respectively. Previous sinus surgery was done in 31.9%, and 15.7% of patients were smokers. The most common presenting complaint was nasal congestion/obstruction, followed by facial pain/headaches and olfactory disturbance. A positive outcome was achieved in 80.5% of patients at 6 months and in 69.7% at 12-month follow-up. Revision surgery within a year was needed in 4.1% of patients. Factors affecting outcome included asthma, smoking, polyposis, previous surgery, and pansinusitis. CONCLUSIONS: Extent of disease, as reflected by polyposis, pansinusitis, and premorbid history, is the most important determinant of outcome. Concomitant changes in ciliary motility secondary to asthma or smoking further impede surgical outcome. Future studies focusing on the disease process of chronic sinusitis are needed.
Authors: Devyani Lal; Ameya A Jategaonkar; Larry Borish; Linda R Chambliss; Sharon H Gnagi; Peter H Hwang; Matthew A Rank; James A Stankiewicz; Valerie J Lund Journal: Rhinology Date: 2016-06 Impact factor: 3.681