| Literature DB >> 9794837 |
S Shresta1, C T Pham, D A Thomas, T A Graubert, T J Ley.
Abstract
CD8+ cytotoxic lymphocytes, natural killer cells and lymphokine-activated killer cells depend primarily on the perforin/granzyme system to kill their targets, while CD4+ T cells utilize Fas and other mechanisms to induce cell death. The molecular mechanisms used by these pathways to induce target cell apoptosis may converge on common death substrates.Entities:
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Year: 1998 PMID： 9794837 DOI： 10.1016/s0952-7915(98)80227-6
Source DB: PubMed Journal: Curr Opin Immunol ISSN： 0952-7915 Impact factor: 7.486