Literature DB >> 9792206

Is ouabain produced by the adrenal gland?

R H Foster1, H Prat, I Rothman.   

Abstract

1. Ouabain or a related stereoisomer, termed endogenous ouabain, has been identified in adrenal cortex tissue and culture medium from adrenocortical cells. 2. Angiotensin II and adrenocorticotropin, the main activators of aldosterone secretion from adrenal glomerulosa cells appear to increase the production of this compound. 3. The purpose of this review is to briefly discuss recent available experimental evidence suggesting that endogenous ouabain is secreted by the zona glomerulosa of the adrenal gland.

Entities:  

Mesh:

Substances:

Year:  1998        PMID: 9792206     DOI: 10.1016/s0306-3623(98)00021-4

Source DB:  PubMed          Journal:  Gen Pharmacol        ISSN: 0306-3623


  2 in total

1.  The trophic effect of ouabain on retinal ganglion cell is mediated by EGF receptor and PKC delta activation.

Authors:  Gustavo de Rezende Corrêa; Karinne Cristinne da Silva Cunha; Aline Araujo dos Santos; Elizabeth Giestal de Araujo
Journal:  Neurochem Res       Date:  2010-05-25       Impact factor: 3.996

2.  Estrogen reduces aldosterone, upregulates adrenal angiotensin II AT2 receptors and normalizes adrenomedullary Fra-2 in ovariectomized rats.

Authors:  Miroslava Macova; Ines Armando; Jin Zhou; Gustavo Baiardi; Dmitri Tyurmin; Ignacio M Larrayoz-Roldan; Juan M Saavedra
Journal:  Neuroendocrinology       Date:  2008-08-04       Impact factor: 4.914

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.