Literature DB >> 9791864

Testicular germ cell tumors: molecular understanding and clinical implications.

S G Lutzker1, N J Barnard.   

Abstract

It was recognized in the 1960s that testicular germ cell tumors were curable with chemotherapeutic drugs. Since that time, newer drugs including cisplatin have increased the cure rate of these tumors to over 80%, even in patients with metastatic disease. Germ cell tumors also exhibit a unique biology and genetics that distinguish them from other solid tumors and might contribute to their routine curability.

Entities:  

Mesh：

Substances：

Year:  1998        PMID： 9791864     DOI： 10.1016/s1357-4310(98)01329-x

Source DB:  PubMed          Journal:  Mol Med Today        ISSN： 1357-4310


  4 in total

1.  Epigenetic silencing of the putative tumor suppressor gene testisin in testicular germ cell tumors.

Authors:  Carsten Kempkensteffen; Frank Christoph; Steffen Weikert; Hans Krause; Jens Köllermann; Martin Schostak; Kurt Miller; Mark Schrader
Journal:  J Cancer Res Clin Oncol       Date:  2006-06-21       Impact factor: 4.553

2.  Testicular Germ Cell Tumors: A Paradigm for the Successful Treatment of Solid Tumor Stem Cells.

Authors:  Caryl J Giuliano; Sarah J Freemantle; Michael J Spinella
Journal:  Curr Cancer Ther Rev       Date:  2006-08-01

3.  DNA methylation profiles delineate epigenetic heterogeneity in seminoma and non-seminoma.

Authors:  M Brait; L Maldonado; S Begum; M Loyo; D Wehle; F F Tavora; L H J Looijenga; J Kowalski; Z Zhang; E Rosenbaum; S Halachmi; G J Netto; M O Hoque
Journal:  Br J Cancer       Date:  2011-11-08       Impact factor: 7.640

4.  Hypermethylation of the 5' CpG island of the gene encoding the serine protease Testisin promotes its loss in testicular tumorigenesis.

Authors:  K J Manton; M L Douglas; S Netzel-Arnett; D R Fitzpatrick; D L Nicol; A W Boyd; J A Clements; T M Antalis
Journal:  Br J Cancer       Date:  2005-02-28       Impact factor: 7.640
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.