Literature DB >> 9790372

Pulmonary edema in obstetric patients is rapidly resolved except in the presence of infection or of nitroglycerin tocolysis after open fetal surgery.

E M DiFederico1, J M Burlingame, S J Kilpatrick, M Harrison, M A Matthay.   

Abstract

OBJECTIVES: This study was designed to determine the etiology, course, and severity of pulmonary edema in obstetric patients in a tertiary care center. STUDY
DESIGN: A retrospective study was carried out on 16,810 deliveries from University of California, San Francisco, 1985-1995. Diagnosis and severity of lung injury were defined by a 4-point system that was based on the chest radiograph, oxygenation, positive end-expiratory pressure, and lung compliance. Resolution of pulmonary edema was defined by improvement in the chest radiograph and hypoxemia (ratio of arterial oxygen tension to inspired oxygen concentration) scores or by extubation.
RESULTS: Pulmonary edema developed in 86 patients, or 0.5% of all obstetric cases. It usually showed extensive air space consolidation on the chest radiograph and arterial hypoxemia. Although 43% of the patients had severe pulmonary dysfunction, the average time to resolution of pulmonary edema was 2.4 days. Only 45% of patients required admission to the intensive care unit and only 15% required intubation and positive-pressure ventilation. Patients with infection (mean of 7.2 days) or fetal surgery (mean of 3.8 days) had the most severe, protracted course.
CONCLUSION: Although obstetric pulmonary edema is associated with extensive radiographic infiltrates and severe hypoxemia, resolution occurs rapidly in most patients, limiting the need for intensive care support.

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Year:  1998        PMID: 9790372     DOI: 10.1016/s0002-9378(98)70190-5

Source DB:  PubMed          Journal:  Am J Obstet Gynecol        ISSN: 0002-9378            Impact factor:   8.661


  6 in total

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2.  Brain malformations in the sheep model of myelomeningocele are similar to those found in human disease: preliminary report.

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3.  Anesthesia for in utero repair of myelomeningocele.

Authors:  Marla Ferschl; Robert Ball; Hanmin Lee; Mark D Rollins
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Review 4.  Modern fetal surgery-a historical review of the happenings that shaped modern fetal surgery and its practices.

Authors:  Lauren L Evans; Michael R Harrison
Journal:  Transl Pediatr       Date:  2021-05

Review 5.  Acute respiratory failure and mechanical ventilation in pregnant patient: A narrative review of literature.

Authors:  Pradeep Kumar Bhatia; Ghansham Biyani; Sadik Mohammed; Priyanka Sethi; Pooja Bihani
Journal:  J Anaesthesiol Clin Pharmacol       Date:  2016 Oct-Dec

6.  Noninvasive positive-pressure ventilation in pregnancy to treat acute pulmonary edema induced by tocolytic agents: a case report.

Authors:  Kotaro Takahashi; Koji Nishijima; Masayuki Yamaguchi; Kensuke Matsumoto; Shunya Sugai; Takayuki Enomoto
Journal:  J Med Case Rep       Date:  2021-03-21
  6 in total

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