Literature DB >> 9790166

Noninsulin-dependent diabetes mellitus as a mitochondrial genomic disease.

C E Mathews1, C D Berdanier.   

Abstract

The genetics of diabetes mellitus is very complex. Although the phenotypes are relatively simple vis-a-vis an abnormal glucose-insulin relationship, a number of genotypes share this phenotype. This review focuses on mutations in the mitochondrial genome that phenotype as diabetes mellitus. Studies in the human and the rat are described.

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Year:  1998        PMID: 9790166     DOI: 10.3181/00379727-219-44321

Source DB:  PubMed          Journal:  Proc Soc Exp Biol Med        ISSN: 0037-9727


  4 in total

1.  Direct linkage of mitochondrial genome variation to risk factors for type 2 diabetes in conplastic strains.

Authors:  Michal Pravenec; Masaya Hyakukoku; Josef Houstek; Vaclav Zidek; Vladimir Landa; Petr Mlejnek; Ivan Miksik; Kristyna Dudová-Mothejzikova; Petr Pecina; Marek Vrbacky; Zdenek Drahota; Alena Vojtiskova; Tomas Mracek; Ludmila Kazdova; Olena Oliyarnyk; Jiaming Wang; Christopher Ho; Nathan Qi; Ken Sugimoto; Theodore Kurtz
Journal:  Genome Res       Date:  2007-08-10       Impact factor: 9.043

2.  mt-Nd2 Allele of the ALR/Lt mouse confers resistance against both chemically induced and autoimmune diabetes.

Authors:  C E Mathews; E H Leiter; O Spirina; Y Bykhovskaya; A M Gusdon; S Ringquist; N Fischel-Ghodsian
Journal:  Diabetologia       Date:  2005-02-04       Impact factor: 10.122

3.  Effect of serum containing Jinmaitong Capsule on rats' Schwann cell apoptosis induced by high glucose concentration.

Authors:  Pu-Yan Wang; Xiao-Chun Liang; Hong Zhang; Li Zhao; Qing Sun; Wen-Zhi Huang; Bo-Wu Li
Journal:  Chin J Integr Med       Date:  2013-07-02       Impact factor: 1.978

4.  Screening of mitochondrial mutations and insertion-deletion polymorphism in gestational diabetes mellitus in the Asian Indian population.

Authors:  Imran Ali Khan; Noor Ahmad Shaik; Nagarjuna Pasupuleti; Srinivas Chava; Parveen Jahan; Qurratulain Hasan; Pragna Rao
Journal:  Saudi J Biol Sci       Date:  2014-11-12       Impact factor: 4.219

  4 in total

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