Literature DB >> 9790135

Characterization of Borrelia burgdorferi strains in Lyme arthritis.

H Eiffert1, A Karsten, R Thomssen, H J Christen.   

Abstract

In the study presented, we investigated whether Lyme arthritis is associated with a particular Borrelia burgdorferi genospecies. Using the PCR technique, in 7/11 samples of synovial fluid of patients with Lyme arthritis a part of the ospA-gene was identified and the strains characterized by sequencing of the amplified DNA. Borrelia burgdorferi sensu stricto was found in 3 patients, B. garinii in 3, and B. afzelii in 1 patient. In conclusion, Lyme arthritis is caused by all 3 human pathogenetic genospecies which are actually known. For clinical practice PCR proved to be a rather insensitive diagnostic method, but may confirm the diagnosis of Lyme arthritis in doubtful cases.

Entities:  

Mesh：

Substances：

Year:  1998        PMID： 9790135     DOI： 10.1080/00365549850160918

Source DB:  PubMed          Journal:  Scand J Infect Dis        ISSN： 0036-5548


  14 in total

1.  Construction and analysis of variants of a polyvalent Lyme disease vaccine: approaches for improving the immune response to chimeric vaccinogens.

Authors:  Christopher G Earnhart; Richard T Marconi
Journal:  Vaccine       Date:  2007-01-17       Impact factor: 3.641

2.  Rapid typing of Borrelia burgdorferi sensu lato species in specimens from patients with different manifestations of Lyme borreliosis.

Authors:  J D Lünemann; S Zarmas; S Priem; J Franz; R Zschenderlein; E Aberer; R Klein; L Schouls; G R Burmester; A Krause
Journal:  J Clin Microbiol       Date:  2001-03       Impact factor: 5.948

Review 3.  Tick-borne encephalopathies : epidemiology, diagnosis, treatment and prevention.

Authors:  Göran Günther; Mats Haglund
Journal:  CNS Drugs       Date:  2005       Impact factor: 5.749

4.  Direct molecular typing of Borrelia burgdorferi sensu lato species in synovial samples from patients with lyme arthritis.

Authors:  B Jaulhac; R Heller; F X Limbach; Y Hansmann; D Lipsker; H Monteil; J Sibilia; Y Piémont
Journal:  J Clin Microbiol       Date:  2000-05       Impact factor: 5.948

5.  Genetic analysis of Borrelia garinii OspA serotype 4 strains associated with neuroborreliosis: evidence for extensive genetic homogeneity.

Authors:  R T Marconi; S Hohenberger; S Jauris-Heipke; U Schulte-Spechtel; C P LaVoie; D Rössler; B Wilske
Journal:  J Clin Microbiol       Date:  1999-12       Impact factor: 5.948

6.  Scored antibody reactivity determined by immunoblotting shows an association between clinical manifestations and presence of Borrelia burgdorferi sensu stricto, B. garinii, B. afzelii, and B. Valaisiana in humans.

Authors:  K Ryffel; O Péter; B Rutti; A Suard; E Dayer
Journal:  J Clin Microbiol       Date:  1999-12       Impact factor: 5.948

Review 7.  Diagnosis of lyme borreliosis.

Authors:  Maria E Aguero-Rosenfeld; Guiqing Wang; Ira Schwartz; Gary P Wormser
Journal:  Clin Microbiol Rev       Date:  2005-07       Impact factor: 26.132

Review 8.  Molecular typing of Borrelia burgdorferi sensu lato: taxonomic, epidemiological, and clinical implications.

Authors:  G Wang; A P van Dam; I Schwartz; J Dankert
Journal:  Clin Microbiol Rev       Date:  1999-10       Impact factor: 26.132

9.  Detection and molecular typing of Borrelia burgdorferi sensu lato in Ixodes ricinus ticks and in different patient samples from southwest Germany.

Authors:  D Schaarschmidt; R Oehme; P Kimmig; R D Hesch; S Englisch
Journal:  Eur J Epidemiol       Date:  2001       Impact factor: 8.082

10.  An ospA-polymerase chain reaction/restriction fragment length polymorphism-based method for sensitive detection and reliable differentiation of all European Borrelia burgdorferi sensu lato species and OspA types.

Authors:  H Michel; B Wilske; G Hettche; G Göttner; C Heimerl; U Reischl; U Schulte-Spechtel; V Fingerle
Journal:  Med Microbiol Immunol       Date:  2003-09-12       Impact factor: 3.402
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.