| Literature DB >> 9789809 |
T Debeir1, H U Saragovi, A C Cuello.
Abstract
Cholinergic neurons are known to respond in vivo to the administration of nerve growth factor (NGF) by a prominent and selective increase of choline acetyl transferase activity and by cholinergic synaptogenesis in the rat brain. By using a synthetic TrkA antagonist we demonstrated that endogenously produced NGF is involved in the continual re-modeling of cholinergic neuronal connections during adulthood, acting through TrkA receptors.Entities:
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Year: 1998 PMID： 9789809 DOI： 10.1016/s0928-4257(98)80011-9
Source DB: PubMed Journal: J Physiol Paris ISSN： 0928-4257