Literature DB >> 9789329

Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase.

C Birchmeier1, E Gherardi.   

Abstract

A number of developmental processes that involve cell migration, growth or morphogenesis depend on extracellular signals. A molecule that provides such signals, known as hepatocyte growth factor/scatter factor (HGF/SF), has attracted considerable interest in recent years because of its distinct structure, mechanism of activation and important roles throughout embryogenesis. This review discusses the main features of HGF/SF and its receptor, the product of the c-met protooncogene, and their role in embryogenesis.

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Year:  1998        PMID： 9789329     DOI： 10.1016/s0962-8924(98)01359-2

Source DB:  PubMed          Journal:  Trends Cell Biol        ISSN： 0962-8924            Impact factor:   20.808


  164 in total

1.  Contact interactions between epitheliocytes and fibroblasts: formation of heterotypic cadherin-containing adhesion sites is accompanied by local cytoskeletal reorganization.

Authors:  T Omelchenko; E Fetisova; O Ivanova; E M Bonder; H Feder; J M Vasiliev; I M Gelfand
Journal:  Proc Natl Acad Sci U S A       Date:  2001-07-10       Impact factor: 11.205

2.  Smad proteins and hepatocyte growth factor control parallel regulatory pathways that converge on beta1-integrin to promote normal liver development.

Authors:  M Weinstein; S P Monga; Y Liu; S G Brodie; Y Tang; C Li; L Mishra; C X Deng
Journal:  Mol Cell Biol       Date:  2001-08       Impact factor: 4.272

3.  Activation of hepatocyte growth factor-met autocrine loop enhances tumorigenicity in a human lung adenocarcinoma cell line.

Authors:  S Yi; M S Tsao
Journal:  Neoplasia       Date:  2000 May-Jun       Impact factor: 5.715

4.  Early clinical development of ARQ 197, a selective, non-ATP-competitive inhibitor targeting MET tyrosine kinase for the treatment of advanced cancers.

Authors:  Alex A Adjei; Brian Schwartz; Edward Garmey
Journal:  Oncologist       Date:  2011-05-31

5.  CD44 is required for two consecutive steps in HGF/c-Met signaling.

Authors:  Véronique Orian-Rousseau; Linfeng Chen; Jonathan P Sleeman; Peter Herrlich; Helmut Ponta
Journal:  Genes Dev       Date:  2002-12-01       Impact factor: 11.361

6.  Distinct recruitment and function of Gab1 and Gab2 in Met receptor-mediated epithelial morphogenesis.

Authors:  Lisa S Lock; Christiane R Maroun; Monica A Naujokas; Morag Park
Journal:  Mol Biol Cell       Date:  2002-06       Impact factor: 4.138

7.  Rho-dependent formation of epithelial "leader" cells during wound healing.

Authors:  T Omelchenko; J M Vasiliev; I M Gelfand; H H Feder; E M Bonder
Journal:  Proc Natl Acad Sci U S A       Date:  2003-09-05       Impact factor: 11.205

Review 8.  Mechanisms of HGF/Met signaling to Brk and Sam68 in breast cancer progression.

Authors:  Alessia Locatelli; Kristopher A Lofgren; Andrea R Daniel; Nancy E Castro; Carol A Lange
Journal:  Horm Cancer       Date:  2012-04       Impact factor: 3.869

9.  Identification of mannose receptor as receptor for hepatocyte growth factor β-chain: novel ligand-receptor pathway for enhancing macrophage phagocytosis.

Authors:  Hiroyuki Ohnishi; Kiyomasa Oka; Shinya Mizuno; Toshikazu Nakamura
Journal:  J Biol Chem       Date:  2012-02-21       Impact factor: 5.157

10.  Autism risk gene MET variation and cortical thickness in typically developing children and adolescents.

Authors:  Alexis Hedrick; Yohan Lee; Gregory L Wallace; Deanna Greenstein; Liv Clasen; Jay N Giedd; Armin Raznahan
Journal:  Autism Res       Date:  2012-10-24       Impact factor: 5.216
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