Literature DB >> 9788982

Combinatorial biosynthesis: lesson learned from nature.

K A Reynolds1.   

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Year:  1998        PMID： 9788982      PMCID： PMC33909          DOI： 10.1073/pnas.95.22.12744

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


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  19 in total

1.  Modular Peptide Synthetases Involved in Nonribosomal Peptide Synthesis.

Authors:  Mohamed A. Marahiel; Torsten Stachelhaus; Henning D. Mootz
Journal:  Chem Rev       Date:  1997-11-10       Impact factor: 60.622

2.  A hybrid modular polyketide synthase obtained by domain swapping.

Authors:  M Oliynyk; M J Brown; J Cortés; J Staunton; P F Leadlay
Journal:  Chem Biol       Date:  1996-10

3.  Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.

Authors:  J F Aparicio; I Molnár; T Schwecke; A König; S F Haydock; L E Khaw; J Staunton; P F Leadlay
Journal:  Gene       Date:  1996-02-22       Impact factor: 3.688

4.  A second type-I PKS gene cluster isolated from Streptomyces hygroscopicus ATCC 29253, a rapamycin-producing strain.

Authors:  X Ruan; D Stassi; S A Lax; L Katz
Journal:  Gene       Date:  1997-12-05       Impact factor: 3.688

5.  Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.

Authors:  P R August; L Tang; Y J Yoon; S Ning; R Müller; T W Yu; M Taylor; D Hoffmann; C G Kim; X Zhang; C R Hutchinson; H G Floss
Journal:  Chem Biol       Date:  1998-02

6.  The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.

Authors:  T Schwecke; J F Aparicio; I Molnár; A König; L E Khaw; S F Haydock; M Oliynyk; P Caffrey; J Cortés; J B Lester
Journal:  Proc Natl Acad Sci U S A       Date:  1995-08-15       Impact factor: 11.205

7.  DNA shuffling by random fragmentation and reassembly: in vitro recombination for molecular evolution.

Authors:  W P Stemmer
Journal:  Proc Natl Acad Sci U S A       Date:  1994-10-25       Impact factor: 11.205

8.  A second branched-chain alpha-keto acid dehydrogenase gene cluster (bkdFGH) from Streptomyces avermitilis: its relationship to avermectin biosynthesis and the construction of a bkdF mutant suitable for the production of novel antiparasitic avermectins.

Authors:  C D Denoya; R W Fedechko; E W Hafner; H A McArthur; M R Morgenstern; D D Skinner; K Stutzman-Engwall; R G Wax; W C Wernau
Journal:  J Bacteriol       Date:  1995-06       Impact factor: 3.490

9.  Ethyl-substituted erythromycin derivatives produced by directed metabolic engineering.

Authors:  D L Stassi; S J Kakavas; K A Reynolds; G Gunawardana; S Swanson; D Zeidner; M Jackson; H Liu; A Buko; L Katz
Journal:  Proc Natl Acad Sci U S A       Date:  1998-06-23       Impact factor: 11.205

10.  Mutational biosynthesis of novel rapamycins by a strain of Streptomyces hygroscopicus NRRL 5491 disrupted in rapL, encoding a putative lysine cyclodeaminase.

Authors:  L E Khaw; G A Böhm; S Metcalfe; J Staunton; P F Leadlay
Journal:  J Bacteriol       Date:  1998-02       Impact factor: 3.490
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  2 in total

Review 1.  Marine tannins: the importance of a mechanistic framework for predicting ecological roles.

Authors:  Thomas M Arnold; Nancy M Targett
Journal:  J Chem Ecol       Date:  2002-10       Impact factor: 2.626

2.  A C35 carotenoid biosynthetic pathway.

Authors:  Daisuke Umeno; Frances H Arnold
Journal:  Appl Environ Microbiol       Date:  2003-06       Impact factor: 4.792
  2 in total

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