Literature DB >> 9785699

The human serotonin-7 receptor pseudogene: variation and chromosome location.

D Nam1, I H Qian, I Kusumi, C Ulpian, T Tallerico, I S Liu, P Seeman.   

Abstract

We report a variation of the pseudogene for the serotonin-7 receptor in human DNA. Human genomic DNA was amplified, using the polymerase chain reaction method and degenerate oligonucleotide primers for serotonin receptor-like genes. A novel gene DNA sequence of 1325 bp was found. Based on nucleotides, this gene is 88% identical to the serotonin-7 receptor coding sequence. Compared with the previously known serotonin-7 receptor pseudogene, this pseudogene has 1 nucleotide deletion and 4 nucleotide mutations. The gene is located on human chromosome 12 at 12p12.3-p13.2.

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Year:  1998        PMID： 9785699      PMCID： PMC1188936     

Source DB:  PubMed          Journal:  J Psychiatry Neurosci        ISSN： 1180-4882            Impact factor:   6.186


  11 in total

1.  Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype.

Authors:  Y Shen; F J Monsma; M A Metcalf; P A Jose; M W Hamblin; D R Sibley
Journal:  J Biol Chem       Date:  1993-08-25       Impact factor: 5.157

2.  Molecular cloning, characterization, and localization of a high-affinity serotonin receptor (5-HT7) activating cAMP formation.

Authors:  M Ruat; E Traiffort; R Leurs; J Tardivel-Lacombe; J Diaz; J M Arrang; J C Schwartz
Journal:  Proc Natl Acad Sci U S A       Date:  1993-09-15       Impact factor: 11.205

3.  Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.

Authors:  J L Plassat; N Amlaiky; R Hen
Journal:  Mol Pharmacol       Date:  1993-08       Impact factor: 4.436

4.  A human serotonin-7 receptor pseudogene.

Authors:  I H Qian; I Kusumi; C Ulpian; T Tallerico; D Nam; I S Liu; M V Seeman; P Seeman
Journal:  Brain Res Mol Brain Res       Date:  1998-01

Review 5.  Dopamine and serotonin receptors: amino acid sequences, and clinical role in neuroleptic parkinsonism.

Authors:  P Seeman; R Corbett; D Nam; H H Van Tol
Journal:  Jpn J Pharmacol       Date:  1996-07

6.  A novel adenylyl cyclase-activating serotonin receptor (5-HT7) implicated in the regulation of mammalian circadian rhythms.

Authors:  T W Lovenberg; B M Baron; L de Lecea; J D Miller; R A Prosser; M A Rea; P E Foye; M Racke; A L Slone; B W Siegel
Journal:  Neuron       Date:  1993-09       Impact factor: 17.173

7.  Cloning of a novel human serotonin receptor (5-HT7) positively linked to adenylate cyclase.

Authors:  J A Bard; J Zgombick; N Adham; P Vaysse; T A Branchek; R L Weinshank
Journal:  J Biol Chem       Date:  1993-11-05       Impact factor: 5.157

8.  An Alu sequence interrupts a human 5-hydroxytryptamine1D receptor pseudogene.

Authors:  T Nguyen; A Marchese; J L Kennedy; A Petronis; S J Peroutka; P H Wu; B F O'Dowd
Journal:  Gene       Date:  1993-02-28       Impact factor: 3.688

9.  A novel rat serotonin receptor: primary structure, pharmacology, and expression pattern in distinct brain regions.

Authors:  W Meyerhof; F Obermüller; S Fehr; D Richter
Journal:  DNA Cell Biol       Date:  1993-06       Impact factor: 3.311

10.  Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors.

Authors:  B L Roth; S C Craigo; M S Choudhary; A Uluer; F J Monsma; Y Shen; H Y Meltzer; D R Sibley
Journal:  J Pharmacol Exp Ther       Date:  1994-03       Impact factor: 4.030
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