| Literature DB >> 9784149 |
E J Gentry1, H B Jampani, A Keshavarz-Shokri, M D Morton, D V Velde, H Telikepalli, L A Mitscher, R Shawar, D Humble, W Baker.
Abstract
Berberine (4) is responsible for the activity of an extract of a commercial root sample of Hydrastis canadensis against multiply drug resistant Mycobacterium tuberculosis. Two new quinic acid feruloyl esters, compounds 2 and 3, have been isolated from the same source along with canadine (1c), 8-oxotetrahydrothalifendine (1), and beta-hydrastine (5). These were found to be inactive. The structures of the new compounds were elucidated from spectral (1H, 13C, HMQC, HMBC, and H-H COSY) and chemical evidences.Entities:
Mesh：
Substances：
Year: 1998 PMID： 9784149 DOI： 10.1021/np9701889
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050