| Literature DB >> 9783214 |
N A Kolchanov1, M P Ponomarenko, A E Kel, A S Frolov, F A Kolpakov, T N Goryachkovsky, O V Kel, E A Ananko, E V Ignatieva, O A Podkolodnaya, V N Babenko, I L Stepanenko, A G Romashchenko, T I Merkulova, D G Vorobiev, S V Lavryushev, A V Kochetov, G B Kolesov, V V Solovyev, L Milanesi, N L Podkolodny, E Wingender, T Heinemeyer.
Abstract
GeneExpress system has been designed to integrate description, analysis, and recognition of eukaryotic regulatory sequences. The system includes 5 basic units: (1) GeneNet contains an object-oriented database for accumulation of data on gene networks and signal transduction pathways and a Java-based viewer that allows an exploration and visualization of the GeneNet information; (2) Transcription Regulation combines the database on transcription regulatory regions of eukaryotic genes (TRRD) and TRRD Viewer; (3) Transcription Factor Binding Site Recognition contains a compilation of transcription factor binding sites (TFBSC) and programs for their analysis and recognition; (4) mRNA Translation is designed for analysis of structural and contextual features of mRNA 5'UTRs and prediction of their translation efficiency; and (5) ACTIVITY is the module for analysis and site activity prediction of a given nucleotide sequence. Integration of the databases in the GeneExpress is based on the Sequence Retrieval System (SRS) created in the European Bioinformatics Institute.Entities:
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Year: 1998 PMID： 9783214
Source DB: PubMed Journal: Proc Int Conf Intell Syst Mol Biol ISSN： 1553-0833