Literature DB >> 978210

Abnormal tissue distribution of lead in amyotrophic lateral sclerosis.

S Conradi, L O Ronnevi, O Vesterberg.   

Abstract

The lead content of cerebrospinal fluid (CSF) was found to be significantly elevated in 12 patients with amyotrophic lateral sclerosis, when compared to 28 control subjects having non-degenerative neurological disorders. The difference could not be explained as being merely secondary to blood-CSF barrier damage. A hypothetical model of the pathogenesis of the disease is advanced and the results are discussed in relation to this model.

Entities:  

Mesh：

Substances：

Year:  1976        PMID： 978210     DOI： 10.1016/0022-510x(76)90175-1

Source DB:  PubMed          Journal:  J Neurol Sci        ISSN： 0022-510X            Impact factor:   3.181


  10 in total

1.  The effect of nerve crush and botulinum toxin on lead uptake in motor axons.

Authors:  R Pamphlett; A Bayliss
Journal:  Acta Neuropathol       Date:  1992       Impact factor: 17.088

2.  Lead concentration in skeletal muscle in amyotrophic lateral sclerosis patients and control subjects.

Authors:  S Conradi; L O Ronnevi; O Vesterberg
Journal:  J Neurol Neurosurg Psychiatry       Date:  1978-11       Impact factor: 10.154

3.  Lead and motor neurone disease.

Authors: 
Journal:  Br Med J       Date:  1978-07-29

4.  Increased plasma levels of lead in patients with amyotrophic lateral sclerosis compared with control subjects as determined by flameless atomic absorption spectrophotometry.

Authors:  S Conradi; L O Ronnevi; O Vesterberg
Journal:  J Neurol Neurosurg Psychiatry       Date:  1978-05       Impact factor: 10.154

5.  Response to penicillamine of lead concentrations in CSF and blood in patients with motor neurone disease.

Authors:  A O House; R J Abbott; D L Davidson; I T Ferguson; J A Lenman
Journal:  Br Med J       Date:  1978-12-16

6.  High accuracy (stable isotope dilution) measurements of lead in serum and cerebrospinal fluid.

Authors:  W I Manton; J D Cook
Journal:  Br J Ind Med       Date:  1984-08

7.  Morbidity and mortality in motor neuron disease: comparison with multiple sclerosis and Parkinson's disease: age and sex specific rates and cohort analyses.

Authors:  T M Li; M Swash; E Alberman
Journal:  J Neurol Neurosurg Psychiatry       Date:  1985-04       Impact factor: 10.154

8.  Urinary excretion of lead and mercury after oral administration of meso-2,3-dimercaptosuccinic acid in patients with motor neurone disease.

Authors:  E S Louwerse; J P Buchet; M A Van Dijk; V J de Jong; R R Lauwerys
Journal:  Int Arch Occup Environ Health       Date:  1995       Impact factor: 3.015

Review 9.  Exposure to environmental toxicants and pathogenesis of amyotrophic lateral sclerosis: state of the art and research perspectives.

Authors:  Francesca Trojsi; Maria Rosaria Monsurrò; Gioacchino Tedeschi
Journal:  Int J Mol Sci       Date:  2013-07-24       Impact factor: 5.923

Review 10.  A meta-analysis of observational studies of the association between chronic occupational exposure to lead and amyotrophic lateral sclerosis.

Authors:  Ming-Dong Wang; James Gomes; Neil R Cashman; Julian Little; Daniel Krewski
Journal:  J Occup Environ Med       Date:  2014-12       Impact factor: 2.162
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.