OBJECTIVE: Determination of the antiquity of spondyloarthropathy by examining the fossil record. METHODS: Fossil collections from the Paleocene and Eocene of North America were systematically examined to determine the occurrence and population frequency of spondyloarthropathy. RESULTS: Spondyloarthropathy was present in three mammalian orders dated at 30 to 50 million years. The frequency was 13% to 50% in the affected genera. CONCLUSIONS: Erosive arthritis of the spondyloarthropathy variety is now documented to have originated at least 40 million years ago in the Paleocene.
OBJECTIVE: Determination of the antiquity of spondyloarthropathy by examining the fossil record. METHODS: Fossil collections from the Paleocene and Eocene of North America were systematically examined to determine the occurrence and population frequency of spondyloarthropathy. RESULTS:Spondyloarthropathy was present in three mammalian orders dated at 30 to 50 million years. The frequency was 13% to 50% in the affected genera. CONCLUSIONS: Erosive arthritis of the spondyloarthropathy variety is now documented to have originated at least 40 million years ago in the Paleocene.
Authors: David Karasik; Serkalem Demissie; L Adrienne Cupples; Douglas P Kiel Journal: J Gerontol A Biol Sci Med Sci Date: 2005-05 Impact factor: 6.053
Authors: David Karasik; Marian T Hannan; L Adrienne Cupples; David T Felson; Douglas P Kiel Journal: J Gerontol A Biol Sci Med Sci Date: 2004-03 Impact factor: 6.053