Literature DB >> 9777790

The pathogenesis of psoriasis and the mechanism of action of tazarotene.

M Duvic1, A T Asano, C Hager, S Mays.   

Abstract

The 3 major features of psoriasis--abnormal differentiation of keratinocytes, hyperproliferation of keratinocytes, and infiltration of inflammatory components into the skin--can be quantified by measuring levels of certain biochemical markers. Psoriasis is associated with upregulation or downregulation of several of these markers. Tazarotene helps to normalize the levels of the markers, thereby bringing about clinical improvement.

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Year:  1998        PMID： 9777790     DOI： 10.1016/s0190-9622(98)70309-3

Source DB:  PubMed          Journal:  J Am Acad Dermatol        ISSN： 0190-9622            Impact factor:   11.527


  8 in total

1.  Evaluation of the effects of IL‑22 on the proliferation and differentiation of keratinocytes in vitro.

Authors:  Le Zhuang; Weiyuan Ma; Jianjun Yan; Hua Zhong
Journal:  Mol Med Rep       Date:  2020-07-20       Impact factor: 2.952

2.  Pathophysiology of Atopic Dermatitis and Psoriasis: Implications for Management in Children.

Authors:  Raj Chovatiya; Jonathan I Silverberg
Journal:  Children (Basel)       Date:  2019-10-04

3.  Decoy receptor 3 is involved in epidermal keratinocyte commitment to terminal differentiation via EGFR and PKC activation.

Authors:  Nan-Lin Wu; Duen-Yi Huang; Shie-Liang Hsieh; Yang-Shia Dai; Wan-Wan Lin
Journal:  Exp Mol Med       Date:  2022-04-27       Impact factor: 12.153

Review 4.  Current and Future Therapies for Psoriasis with a Focus on Serotonergic Drugs.

Authors:  Ana M Martins; Andreia Ascenso; Helena Margarida Ribeiro; Joana Marto
Journal:  Mol Neurobiol       Date:  2020-02-15       Impact factor: 5.590

Review 5.  Topical Therapies in Psoriasis.

Authors:  R Torsekar; Manjyot M Gautam
Journal:  Indian Dermatol Online J       Date:  2017 Jul-Aug

6.  Urticarial Reaction to Ustekinumab During the Treatment of Plaque Psoriasis in a Hepatitis C-Positive Patient.

Authors:  Christopher H Chu; Charles Davis
Journal:  Drug Saf Case Rep       Date:  2017-12

Review 7.  Psoriasis: From Pathogenesis to Pharmacological and Nano-Technological-Based Therapeutics.

Authors:  Robert Gironés Petit; Amanda Cano; Alba Ortiz; Marta Espina; Josefina Prat; Montserrat Muñoz; Patrícia Severino; Eliana B Souto; Maria L García; Montserrat Pujol; Elena Sánchez-López
Journal:  Int J Mol Sci       Date:  2021-05-07       Impact factor: 5.923

Review 8.  Fixed-Combination Halobetasol Propionate and Tazarotene in the Treatment of Psoriasis: Narrative Review of Mechanisms of Action and Therapeutic Benefits.

Authors:  Mark G Lebwohl; Emil A Tanghetti; Linda Stein Gold; James Q Del Rosso; Nelly K Gilyadov; Abby Jacobson
Journal:  Dermatol Ther (Heidelb)       Date:  2021-06-09
  8 in total

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