Literature DB >> 9776114

Low frequency of HLA-B27 and scarcity of ankylosing spondylitis in a Zairean Bantu population.

K Mbayo1, J M Mbuyi-Muamba, A Z Lurhuma, L Halle, C Kaplan, J Dequeker.   

Abstract

Ankylosing spondylitis (AS) is an inflammatory rheumatic disease which is thought to be rarely seen in African Blacks. Its genetic predisposition has been stressed in Caucasians where the HLA-B27 antigen is firmly linked to the disease. In the present study, HLA-B27 antigen was determined in 146 individuals of Bantu root. Only one of these subjects was found to possess HLA-B27 antigen. This study correlates the low frequency of HLA-B27 with the observed scarcity of AS in patients attending a clinic in Kinshasa for osteoarticular diseases.

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Year:  1998        PMID： 9776114     DOI： 10.1007/bf01451011

Source DB:  PubMed          Journal:  Clin Rheumatol        ISSN： 0770-3198            Impact factor:   2.980


  9 in total

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Journal:  Nature       Date:  1964-12-05       Impact factor: 49.962

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Review 3.  Guilt by association: HLA-B27 and ankylosing spondylitis.

Authors:  R Benjamin; P Parham
Journal:  Immunol Today       Date:  1990-04

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Authors:  J Sieper; G Kingsley
Journal:  Immunol Today       Date:  1996-04

5.  HLA-A, B, C, DR and DQ polymorphisms in three South African population groups: South African Negroes, Cape Coloureds and South African Caucasoids.

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Journal:  Tissue Antigens       Date:  1988-03

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Authors:  S O Larsen
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Authors:  R C Okoye; E Williams; A Alonso; P Doyle; J Awad; C Navarrete; D Jaraquemada; W E Ollier; H Festenstein
Journal:  Tissue Antigens       Date:  1985-03

8.  Ankylosing spondylitis in two Zaïrian brothers.

Authors:  J M Mbuyi-Muamba; N Malonda; O Yuma
Journal:  Clin Rheumatol       Date:  1993-06       Impact factor: 2.980

9.  Rheumatic disorders in Zimbabwe: a prospective analysis of patients attending a rheumatic diseases clinic.

Authors:  M Stein; P Davis
Journal:  Ann Rheum Dis       Date:  1990-06       Impact factor: 19.103
  9 in total
  4 in total

Review 1.  Spondyloarthritis in sub-Saharan Africa.

Authors:  Mohammed Tikly; Panganani Njobvu; Paul McGill
Journal:  Curr Rheumatol Rep       Date:  2014-06       Impact factor: 4.592

2.  Clinical and epidemiological features of rheumatic diseases in patients attending the university hospital in Kinshasa.

Authors:  J J Malemba; J M Mbuyi-Muamba
Journal:  Clin Rheumatol       Date:  2007-06-02       Impact factor: 3.650

3.  Clinical patterns of juvenile idiopathic arthritis in Zambia.

Authors:  James Chipeta; Panganani Njobvu; Somwe Wa-Somwe; Chifumbe Chintu; Paul E McGill; Richard Bucala
Journal:  Pediatr Rheumatol Online J       Date:  2013-09-14       Impact factor: 3.054

4.  Spondyloarthritis in the Democratic Republic of the Congo: a prospective hospital-based study.

Authors:  Pierrot Lebughe; Kurt de Vlam; Rene Westhovens; Jean-Marie Mbuyi-Muamba; Jean Jacques Malemba
Journal:  BMJ Open       Date:  2018-05-09       Impact factor: 2.692
  4 in total

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