Literature DB >> 9774781

An association study of a functional polymorphism of the serotonin transporter gene with personality and psychiatric symptoms.

A F Jorm1, A S Henderson, P A Jacomb, H Christensen, A E Korten, B Rodgers, X Tan, S Easteal.   

Abstract

A functional polymorphism in the regulatory region of the serotonin transporter gene has been reported to be associated with anxiety-related personality traits. We attempted to replicate this finding in an association study involving 759 Caucasians selected from the general Australian population. We found no associations with personality traits (including neuroticism, negative affect and behavioral inhibition), anxiety and depressive symptoms, or alcohol misuse.

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Year:  1998        PMID： 9774781     DOI： 10.1038/sj.mp.4000424

Source DB:  PubMed          Journal:  Mol Psychiatry        ISSN： 1359-4184            Impact factor:   15.992


  12 in total

1.  Testing the null hypothesis: comments on 'Culture-gene coevolution of individualism-collectivism and the serotonin transporter gene'.

Authors:  Dan T A Eisenberg; M Geoffrey Hayes
Journal:  Proc Biol Sci       Date:  2010-09-22       Impact factor: 5.349

2.  5-HTTLPR genotype and anxiety-related personality traits: a meta-analysis and new data.

Authors:  Marcus R Munafò; Nelson B Freimer; Whitney Ng; Roel Ophoff; Juha Veijola; Jouko Miettunen; Marjo-Riitta Järvelin; Anja Taanila; Jonathan Flint
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2009-03-05       Impact factor: 3.568

3.  A serotonin transporter gene intron 2 polymorphic region, correlated with affective disorders, has allele-dependent differential enhancer-like properties in the mouse embryo.

Authors:  A MacKenzie; J Quinn
Journal:  Proc Natl Acad Sci U S A       Date:  1999-12-21       Impact factor: 11.205

Review 4.  The genetics of anxiety-related negative valence system traits.

Authors:  Jeanne E Savage; Chelsea Sawyers; Roxann Roberson-Nay; John M Hettema
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2016-05-19       Impact factor: 3.568

Review 5.  Implications of genetic research on the role of the serotonin in depression: emphasis on the serotonin type 1A receptor and the serotonin transporter.

Authors:  Alexander Neumeister; Theresa Young; Juergen Stastny
Journal:  Psychopharmacology (Berl)       Date:  2004-07-13       Impact factor: 4.530

6.  Effects of environmental stress and gender on associations among symptoms of depression and the serotonin transporter gene linked polymorphic region (5-HTTLPR).

Authors:  Beverly H Brummett; Stephen H Boyle; Ilene C Siegler; Cynthia M Kuhn; Allison Ashley-Koch; Charles R Jonassaint; Stephan Züchner; Ann Collins; Redford B Williams
Journal:  Behav Genet       Date:  2007-10-23       Impact factor: 2.805

Review 7.  The serotonergic system and anxiety.

Authors:  Joshua A Gordon; Rene Hen
Journal:  Neuromolecular Med       Date:  2004       Impact factor: 3.843

Review 8.  The genetic relationship of personality to major depression and schizophrenia.

Authors:  Ayman H Fanous; Kenneth S Kendler
Journal:  Neurotox Res       Date:  2004       Impact factor: 3.911

9.  Variants of the serotonin transporter gene and NEO-PI-R Neuroticism: No association in the BLSA and SardiNIA samples.

Authors:  Antonio Terracciano; Lenuta Balaci; Jason Thayer; Matthew Scally; Sarah Kokinos; Luigi Ferrucci; Toshiko Tanaka; Alan B Zonderman; Serena Sanna; Nazario Olla; Maria Antonietta Zuncheddu; Silvia Naitza; Fabio Busonero; Manuela Uda; David Schlessinger; Gonçalo R Abecasis; Paul T Costa
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2009-12-05       Impact factor: 3.568

10.  Association of the serotonin transporter gene, neuroticism and smoking behaviours.

Authors:  Colin O'Gara; Jo Knight; John Stapleton; Jason Luty; Ben Neale; Matt Nash; Patricia Heuzo-Diaz; Farzana Hoda; Sarah Cohen; Gay Sutherland; David Collier; Pak Sham; David Ball; Peter McGuffin; Ian Craig
Journal:  J Hum Genet       Date:  2008-01-10       Impact factor: 3.172
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