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Literature DB >> 9774617

Helicobacter pylori cagA status and s and m alleles of vacA in isolates from individuals with a variety of H. pylori-associated gastric diseases.

D G Evans¹, D M Queiroz, E N Mendes, D J Evans.

Abstract

The cagA gene was detected in 100% of 16 Helicobacter pylori isolates from patients with gastric carcinoma versus 78% of 18 isolates from patients with duodenal ulcers (P = 0.344) and only 64% of 22 isolates from patients with gastritis only (P = 0.005) in Brazil. Also, there was a significant association between isolation of cagA+ s1-type vacA H. pylori in cases of stomach cancer and ulcers as opposed to cases of gastritis only (P = 0.004), but this was not true in Houston (P = 0.238), where 94% of all isolates were cagA+.

Entities: Disease Species

Mesh：

Substances：

Year: 1998 PMID： 9774617 PMCID： PMC105353

Source DB: PubMed Journal: J Clin Microbiol ISSN： 0095-1137 Impact factor: 5.948

21 in total

1. Diversity in the variable region of Helicobacter pylori cagA gene involves more than simple repetition of a 102-nucleotide sequence.

Authors: D J Evans; D M Queiroz; E N Mendes; D G Evans
Journal: Biochem Biophys Res Commun Date: 1998-04-28 Impact factor: 3.575

2. Analysis and typing of the vacA gene from cagA-positive strains of Helicobacter pylori isolated in Japan.

Authors: Y Ito; T Azuma; S Ito; H Miyaji; M Hirai; Y Yamazaki; F Sato; T Kato; Y Kohli; M Kuriyama
Journal: J Clin Microbiol Date: 1997-07 Impact factor: 5.948

3. cagA-positive Helicobacter pylori populations in China and The Netherlands are distinct.

Authors: A van der Ende; Z J Pan; A Bart; R W van der Hulst; M Feller; S D Xiao; G N Tytgat; J Dankert
Journal: Infect Immun Date: 1998-05 Impact factor: 3.441

4. Analysis of expression of CagA and VacA virulence factors in 43 strains of Helicobacter pylori reveals that clinical isolates can be divided into two major types and that CagA is not necessary for expression of the vacuolating cytotoxin.

Authors: Z Xiang; S Censini; P F Bayeli; J L Telford; N Figura; R Rappuoli; A Covacci
Journal: Infect Immun Date: 1995-01 Impact factor: 3.441

5. Ordered cosmid library and high-resolution physical-genetic map of Helicobacter pylori strain NCTC11638.

Authors: N O Bukanov; D E Berg
Journal: Mol Microbiol Date: 1994-02 Impact factor: 3.501

6. Country-specific constancy by age in cagA+ proportion of Helicobacter pylori infections.

Authors: G I Pérez-Pérez; N Bhat; J Gaensbauer; A Fraser; D N Taylor; E J Kuipers; L Zhang; W C You; M J Blaser
Journal: Int J Cancer Date: 1997-07-29 Impact factor: 7.396

7. Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer.

Authors: A Covacci; S Censini; M Bugnoli; R Petracca; D Burroni; G Macchia; A Massone; E Papini; Z Xiang; N Figura
Journal: Proc Natl Acad Sci U S A Date: 1993-06-15 Impact factor: 11.205

8. Variants of the 3' region of the cagA gene in Helicobacter pylori isolates from patients with different H. pylori-associated diseases.

Authors: Y Yamaoka; T Kodama; K Kashima; D Y Graham; A R Sepulveda
Journal: J Clin Microbiol Date: 1998-08 Impact factor: 5.948

Review 9. Helicobacter pylori phenotypes associated with peptic ulceration.

Authors: M J Blaser
Journal: Scand J Gastroenterol Suppl Date: 1994

10. Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach.

Authors: M J Blaser; G I Perez-Perez; H Kleanthous; T L Cover; R M Peek; P H Chyou; G N Stemmermann; A Nomura
Journal: Cancer Res Date: 1995-05-15 Impact factor: 12.701

18 in total

1. Helicobacter pylori vacA genotypes and cagA status and their relationship to associated diseases.

Authors: Peng Hou; Zhen-Xing Tu; Guo-Ming Xu; Yan-Fang Gong; Xu-Hui Ji; Zhao-Shen Li
Journal: World J Gastroenterol Date: 2000-08 Impact factor: 5.742

2. Helicobacter pylori infection is associated with a high incidence of intestinal metaplasia in the gastric mucosa of patients at inner-city hospitals in New York.

Authors: J Schneller; R Gupta; J Mustafa; R Villanueva; E W Straus; R D Raffaniello
Journal: Dig Dis Sci Date: 2006-10 Impact factor: 3.199

3. Helicobacter pylori genotypes may determine gastric histopathology.

Authors: C Nogueira; C Figueiredo; F Carneiro; A T Gomes; R Barreira; P Figueira; C Salgado; L Belo; A Peixoto; J C Bravo; L E Bravo; J L Realpe; A P Plaisier; W G Quint; B Ruiz; P Correa; L J van Doorn
Journal: Am J Pathol Date: 2001-02 Impact factor: 4.307

4. Consensus and variable region PCR analysis of Helicobacter pylori 3' region of cagA gene in isolates from individuals with or without peptic ulcer.

Authors: C A Rota; J C Pereira-Lima; C Blaya; N B Nardi
Journal: J Clin Microbiol Date: 2001-02 Impact factor: 5.948

5. New pathogenicity marker found in the plasticity region of the Helicobacter pylori genome.

Authors: Adriana Santos; Dulciene Maria Magalhães Queiroz; Armelle Ménard; Armelle Marais; Gifone Aguiar Rocha; Celso Affonso Oliveira; Ana Margarida Miguel Ferreira Nogueira; Milton Uzeda; Francis Mégraud
Journal: J Clin Microbiol Date: 2003-04 Impact factor: 5.948

6. Comparison of genomic structures and antigenic reactivities of orthologous 29-kilodalton outer membrane proteins of Helicobacter pylori.

Authors: A Sumie; T Yamashiro; K Nakashima; M Nasu; M Watanabe; A Nishizono
Journal: Infect Immun Date: 2001-11 Impact factor: 3.441