L Capps1, G Peng, M Doyle, W El-Sadr, J D Neaton. 1. Department of Medicine, Harlem Hospital, Columbia University College of Physicians and Surgeons, New York, USA.
Abstract
BACKGROUND AND OBJECTIVES: Limited prospective data are available on sexually transmitted infections (STIs) among HIV-infected patients. The incidence and predictors of STIs were assessed among HIV-infected women enrolled in a clinical trial. STUDY DESIGN: Prospective cohort of 323 women. RESULTS: Sixty-five percent had at least one STI based on history and/or examination at baseline. Most conditions identified at baseline were based on patient history; only 10 of 123 women with no history of an STI (8.1%) had one identified upon examination. During a median follow-up of 2.1 years, 25% developed a new/recurrent STI. Being African-American (odds ratio [OR] = 4.22, 95% confidence interval [CI]: 1.45-12.26), reporting sex with an intravenous drug user as an HIV risk behavior (OR = 2.29, 95% CI: 1.34-3.92), and a history/presence of STIs at baseline (OR = 1.79, 95% CI: 1.01-3.19) were factors associated with significantly increased risk of STI's. CONCLUSIONS: A substantial proportion of women developed new STIs during the course of the clinical trial. Prevention efforts should be emphasized among high risk HIV-infected patients.
BACKGROUND AND OBJECTIVES: Limited prospective data are available on sexually transmitted infections (STIs) among HIV-infectedpatients. The incidence and predictors of STIs were assessed among HIV-infectedwomen enrolled in a clinical trial. STUDY DESIGN: Prospective cohort of 323 women. RESULTS: Sixty-five percent had at least one STI based on history and/or examination at baseline. Most conditions identified at baseline were based on patient history; only 10 of 123 women with no history of an STI (8.1%) had one identified upon examination. During a median follow-up of 2.1 years, 25% developed a new/recurrent STI. Being African-American (odds ratio [OR] = 4.22, 95% confidence interval [CI]: 1.45-12.26), reporting sex with an intravenous drug user as an HIV risk behavior (OR = 2.29, 95% CI: 1.34-3.92), and a history/presence of STIs at baseline (OR = 1.79, 95% CI: 1.01-3.19) were factors associated with significantly increased risk of STI's. CONCLUSIONS: A substantial proportion of women developed new STIs during the course of the clinical trial. Prevention efforts should be emphasized among high risk HIV-infectedpatients.
Authors: Carol E Golin; Jo Anne Earp; Catherine A Grodensky; Shilpa N Patel; Chirayath Suchindran; Megha Parikh; Seth Kalichman; Kristine Patterson; Heidi Swygard; E Byrd Quinlivan; Kemi Amola; Zulfiya Chariyeva; Jennifer Groves Journal: AIDS Behav Date: 2012-07