Literature DB >> 9772707

[Two new steroidal saponins from Allium sativum and their inhibitory effects on blood coagulability].

J P Peng1, H Chen, Y Q Qiao, L R Ma, T Narui, H Suzuki, T Okuyama, H Kobayashi.   

Abstract

Six compunds were isolated from the fresh bulbs of Allium sativum L (garlic). Their structures were elucidated as proto-iso-eruboside-B (I), eruboside-B (II), iso-eruboside-B (III), sativioside C (IV), adenosine (V) and tryptophan (VI). I and III are new steroidal saponins. This paper deals with the structural determination of I and III and their effects on platelet aggregation, blood coagulation and fibrinolysis in vitro.

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Year:  1996        PMID: 9772707

Source DB:  PubMed          Journal:  Yao Xue Xue Bao        ISSN: 0513-4870


  5 in total

1.  Anticancer Activity of Saponins from Allium chinense against the B16 Melanoma and 4T1 Breast Carcinoma Cell.

Authors:  Zhihui Yu; Tong Zhang; Fengjuan Zhou; Xiuqing Xiao; Xuezhi Ding; Hao He; Jie Rang; Meifang Quan; Ting Wang; Mingxing Zuo; Liqiu Xia
Journal:  Evid Based Complement Alternat Med       Date:  2015-06-03       Impact factor: 2.629

Review 2.  Steroidal saponins from the genus Allium.

Authors:  Danuta Sobolewska; Klaudia Michalska; Irma Podolak; Karolina Grabowska
Journal:  Phytochem Rev       Date:  2014-10-08       Impact factor: 5.374

Review 3.  Chemistry of aged garlic: Diversity of constituents in aged garlic extract and their production mechanisms via the combination of chemical and enzymatic reactions.

Authors:  Yukihiro Kodera; Masahiro Kurita; Masato Nakamoto; Toshiaki Matsutomo
Journal:  Exp Ther Med       Date:  2019-12-27       Impact factor: 2.447

Review 4.  Roles and mechanisms of garlic and its extracts on atherosclerosis: A review.

Authors:  Min Li; Wingyan Yun; Guibin Wang; Anqi Li; Jing Gao; Qingyong He
Journal:  Front Pharmacol       Date:  2022-10-03       Impact factor: 5.988

5.  Antiatherosclerosis Properties of Total Saponins of Garlic in Rats.

Authors:  Qing Miao; Ruihai Wang; Dong Bai; Xin Xue; Jing Xu; Xiaoxin Sun; Limei Liu
Journal:  Evid Based Complement Alternat Med       Date:  2020-02-27       Impact factor: 2.629

  5 in total

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